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Innovative MALDI-TOF and TOF/TOF technology for reliable and detailed protein characterization, high resolution MALDI imaging and validated biomarker discovery. Patented smartbeam™ laser technology is a must for MALDI Molecular Imaging and gives access to superior performance in any Proteomics project.
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Results. Better. Faster. Take your GC/MS to the limit with the Clarus® 600 Gas Chromatograph/Mass Spectrometer (GC/MS). It delivers the performance and throughput you require with the ruggedness you demand.
The compact Clarus 600 GC/MS, with its advanced electronics, features the widest mass range and best-in-class detection limits of any quadrupole MS. Our high-speed scanning delivers far better peak integrity and accuracy. Its gas chromatograph has the fastest heat-up and cool-down oven in a conventional GC. Multiple pumping options offer an instrument for every lab’s needs.
- State-of-the-art electronics provide fast scanning and increased
productivity
- Plug-and-play ion source - click here for demo
- Multiple pumping options offer an instrument for every lab’s needs
- NEW Marathon™ Filament delivers long life even under the most difficult
chromatography conditions
- TurboMass GC/MS software delivers easy environmental compliance
- Fastest heat-up and cool-down oven in conventional GC
PerkinElmer—the clear choice in gas chromatography.
Get results—better and faster with the new Clarus 600 GC/MS.
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The DSQ II with the FOCUS GC is a space-saving quadrupole GC/MS designed for laboratories wanting the ultimate in GC/MS performance but having limited space and funds. The system combines the advanced, next-generation curved optics of the industry-leading DSQ II with the small footprint of the FOCUS GCto create a compact but powerful analyzer for environmental, petrochemical, forensics, toxicology and QA/QC applications.
The FOCUS DSQ II is equipped with the next-generation DuraBrite™ XL source and innovative DynaMax XR detection system. This source and detector combination allows detection of smaller concentrations of compounds in difficult matrices, which translates into less prep time, smaller injection volumes, less sample usage, more confidence - real productivity. No more background noise from excited neutrals, no more sample contamination of the sensitive quadrupoles; the curved pre-filter efficiently removes it.
The FOCUS DSQ II is small in size, but big on results. Enhance your productivty with the vacuum interlockfor "no-vent" source maintenance or add an autosampler for unattended sample analysis.
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240-MS GC Ion Trap
Leading the way in GC/MS Analysis
The Varian 240-MS Ion Trap, together with the Varian 450-GC, delivers unparalleled capabilities for both research and routine applications with reliability you expect from an industry leader.
The Varian 240-MS Provides:
- Unsurpassed sensitivity (200 femtogram OFN)
- Less maintenance and high reliability to deliver maximum productivity
- Accurate identification and quantification of trace analytes
- A unique choice of configurations with internal and/or external ionization
- Intuitive software that makes operation simple
- Powerful MS/MS and CI options
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225-MS GC Ion Trap
The True Benchtop GC/MS System
The Varian 225-MS is the world's first mass spectrometer to enclose all of its components, including the foreline pump, in one compact design. For laboratories where space limitations restrict analytical capacity, the Varian 225-MS GC Ion Trap delivers excellent sensitivity and selectivity in an extremely compact unit.
The self-contained vacuum module yields a number of significant benefits:
Because the turbomolecular pump is closer to the foreline pump, it can work at lower speeds and operating temperatures. THis reduces the background which allows improved sensitivity.
For convenience, the module does not require oil changes during its lifetime.
The much quieter vacuum module reduces noise in the laboratory.
Elimination of the hose from the foreline pump to the turbomolecular pump reduces the space requirement significantly.
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Performance, productivity and confidence.
Welcome to the next generation of the industry-proven Agilent 5975 Series MSD -— the most popular GC/MS of all time. The Agilent 5975C inert MSD with its new Triple-Axis Detector gives you innovative design features that boost your lab’s productivity and advanced analytical capabilities that enhance your results—and your confidence. In addition to delivering better MS resolution and the lowest mass deviation available, the system offers superior sensitivity and spectral integrity. Advanced analysis routines let you get more information from every run, and the latest version of automated spectral deconvolution, identification, and quantification software provides higher quality analyses with even less operator time and attention.
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The new Thermo Scientific LTQ Orbitrap Discovery provides access to the breakthrough Orbitrap™ technology for a wide range of labs. The robust, powerful and cost-effective system is ideally suited for general proteomics and metabolism applications, offering a superior alternative to Q-TOF systems. Featuring high resolution and excellent accurate mass capabilities, this hybrid LC-MS system achieves high throughput label-free profiling for differential expression while the MSn capability makes the instrument ideal for small molecule characterization and structural elucidation. The LTQ Orbitrap Discovery is a highly sensitive system with up to 30K resolution power and an exceptional scan rate, enabling the separation of trace level, isobaric analytes.
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LC Mass Spectrometer: Ion Trap and Quadrupole
500-MS LC Ion Trap
By delivering excellent sensitivity over the entire mass range in full scan mode, and exceptional MS/MS and MSn capabilities, the Varian 500-MS quickly provides superior information for even the most complex sample matrices.
320-MS Triple Quadrupole
The Varian 320-MS provides femtogram sensitivity, a 2000 m/z mass range and a choice of chromatographic and ionization configurations to match your budget and your needs – all in less than 72 cm (28 inches) of linear bench space
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Unprecedented sensitivity and value
Whether you are quantifying pharmaceutical candidates, measuring trace-level environmental or food contaminants, or confirming biomarkers, the Agilent 6400 Series Triple Quadrupole LC/MS systems offer greater sensitivity, productivity, and value than ever before. The new 6460 with Agilent Jet Stream thermal gradient focusing technology provides maximum sensitivity – breaking the femtogram barrier for many compounds. Or choose the incredible value of the 6410 with femtogram-level limits of detection, Agilent reliability, and lab-friendly ease of use.
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UltiMate UHPLC systems with MSQ Plus single quadrupole mass spectrometric detection are easy to use. The UltiMate System's Wellness technology, automatic calibration of the MS detector, and self-cleaning ion source allow for continuous routine operation without the need for frequent cleaning or maintenance. The complete system requires very little setup or fine-tuning to achieve optimum sensitivity. You no longer have to learn two software packages to operate your LC/MS system. Chromeleon® LC/MS software provides single-software method setup and instrument control, powerful UV and MS data analysis, and fully integrated reporting.
With Dionex Intelligent LC (LCi) solutions you can get more out of your LC/MS investment. Technologies such as tandem chromatography allow you to increase sample throughput up to 100%. Other advanced chromatography techniques like 2-D LC or on-line SPE-LC are also available for the UltiMate 3000 LC/MS system, allowing you to automate analyses in your laboratory like never before.
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LC/MS
LC/MS single quadrupole mass analyser product family including mass directed fraction collection using prep LC/MS and web enabled software.
- LCMS 2010A Advanved
- Mass directed purification
- PsiPort™ mass directed auto-purification software
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TwinMS
The TwinMS has two V&F IMR mass spectrometers built-in that can be operated in parallel or series depending on the application requirements. High speed trace emission analysis is the foundation for all V&F mass spectrometers. The added features of the TwinMS allows for simultaneous measurement of pre- and post catalyst and ultra high speed reaction measurement capabilities. These added features can help trim overall R&D costs by reducing expensive test cell time.
Instrument operation is based on quadrupole mass spectrometry with IMR technology. This combination allows for unrivalled performance in sensitivity, speed, selectivity and robust and reliable operation in industrial use.
Attributes:
Ultra-fast, multi-component analysis in ppm and ppb area
Two mode operation
2 gas channels can be measured simultaneously for real time analysis of up to 6 compounds per channel
Fast switching between 2 gas channels with fast measurement of up to 20 components on the 2 parallel operated mass spectrometers
Simultaneous pre- and post catalyst capabilities provides substantial cost savings through reduced test cell runs
Excellent response and reproducibility
Typical detection limit in the ppb area
3 to 4 decades dynamic range
Low operating costs
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Superior Q-TOF performance for greater analytical confidence
Using proprietary True Hi-Def TOF technology, Agilent’s 6520 and 6530 bring an unrivaled combination of mass accuracy and resolution, sensitivity, acquisition speed, and in-spectrum dynamic range to your toughest research challenges. The new Agilent 6530 Accurate-Mass Q-TOF LC/MS with Agilent Jet Stream thermal gradient focusing technology increases sensitivity by a further 5X for even greater analytical confidence. All 6500 Series instruments feature the powerful, compound-centric MassHunter Workstation software with its unsurpassed data mining and qualitative and quantitative data analysis capabilities.
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The micrOTOF™ provides powerful exact mass measurements in an easy-to-use benchtop package. Featuring excellent mass resolution and mass accuracy in combination with true isotopic pattern, micrOTOF is the perfect choice for straight-forward formula determination of small molecules, quality control of intact proteins, and metabolic studies.
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FTMS Flexibility and Performance for the Most Challenging Problems
FTMS is synonymous with performance. The apex-ultra combines the power of FTMS with the latest quadrupole technology (complete with linear ion trapping modes) and superb multipole collision cell for a quantum leap in analytical capability. The unique geometry provides facile and efficient precursor mass selection with collision induced dissociation in the Qh "front end" to the FTMS for on-the-fly LC-MS/FTMS analysis. Moreover, the Qh “front end” to the FTMS provides the added functionality for the enrichment of low abundant species via mass selective accumulation.
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General description :
Expanding the capabilities of ICP-MS
The ELAN® DRC-e ICP-MS is a perfect fit for laboratories needing superior performance and low maintenance at an outstanding price. The ELAN DRC-e uses Dynamic Reaction Cell™ (DRC™) technology to eliminate polyatomic interferences, while innovative Axial Field Technology provides increased speed and stability. The ELAN DRC-e instrument is the ideal choice for laboratories facing the challenges of throughput and detection limits found in today's environmental samples.
Worry-free operation in all types of matrices
The ELAN DRC-e uses the same robust HF-resistant sample introduction system used on the ELAN 9000 system for worry-free performance in virtually any matrix. To ensure minimal maintenance, the ELAN DRC-e includes quick-change cones that resist clogging and drift. Plus, the reaction cell in the ELAN DRC-e is maintenance-free, eliminating the need for time-consuming cell-maintenance procedures.
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Quadrupole ICP-MS
Thermo Scientific XSERIES 2 ICP-MS - The Thermo Scientific XSERIES 2 ICP-MS with advanced H2/He collision cell technology, licensed from Battelle, provides uncompromised multielement analysis for all elements including Ca, Fe, As and Se – and represents the most comprehensive quadrupole ICP-MS platform for high performance across the entire periodic table. Alongside proven high matrix tolerance, the XSERIES 2 operates with 10x less background noise than the nearest competitor – ensuring results of the highest analytical quality.
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Introducing the 810/820-MS
Inductively Coupled Plasma-Mass Spectrometers (ICP-MS)
Varian, Inc. continues to find new and novel ways to meet your changing needs. When you buy a Varian ICP-MS, you’re buying more than just an instrument. You’re buying a relationship with one of the most respected and experienced instrument companies in the world.
If you've ever wished that ICP-MS could be simpler, wish no
more. The Varian 810-MS and 820-MS make ICP-MS effortless.
No matter what your requirements, with a Varian ICP-MS,
you can tackle any application with ease.
Varian 820-MS
In addition to all the features of the 810-MS, the 820-MS features Varian's unique collision reaction interface (CRI)* system, which provides simple, routine removal of troublesome spectroscopic interferences. The result is faster, more flexible interference-free analysis without the worry of complex multipole or scanning quadrupole ion guides or cells. And, by coupling autotuning of all instrument parameters, including CRI gases, instrument productivity is greatly enhanced.
Varian 810-MS
The Varian 810-MS delivers high sample throughput and the ultimate in analytical performance. Core to this instrument is Varian's patented high-efficiency 90 degree ion optics and double off-axis quadrupoles, which deliver exceptionally low background noise and unmatched sensitivity - at more than 1 million counts per second for 1 microgram/liter.
For samples that don't require CRI, the Varian 810-MS
is an ideal instrument with industry leading sensitivity for
trace and major elemental analysis.
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From routine applications to cutting edge research, the Agilent 7500 Series is task-ready. Since the introduction of the world's first Benchtop ICP-MS in 1994, Agilent has led the way in important ICP-MS innovations making the 7500 Series the current state of the art in ICP-MS. The 7500 Series delivers the highest levels of performance for trace metals analysis, while retaining ease of use, flexibility and reliability through automation and excellence in design. Furthermore, our great products are backed by a large team of support specialists - on-hand to help you get the most from your instrument.
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Ion Mobility Spectrometry is the science behind the IONSCAN products
Ion Mobility Spectrometry, or IMS, is an instrumental analytical method that is similar to Time-of-Flight MS. Instead of responding to molecular fragments, however, IMS uses soft ionization. Ionized molecules travel through a drift tube at distinct speeds that are related to their mass and geometry. Selectable positive and negative ionization enhances identification or sensitivity.
The ions in question are generated by atmospheric-pressure chemical ionization. Sample material is heated to yield a vapor that is swept into a small drift chamber where a beta radiation source ionizes the molecules. The resulting ions – separated according to size, mass and geometry – accelerate towards a detector.
On impact, each ion generates a specific signal, which is a function of ion mobility. Mobility (K) is determined from the drift velocity (vd) attained by ions in a weak electric field (E) in the drift tube, according to the equation, vd = K x E. The distribution of these signals forms an ion spectrum, with an ion mobility band corresponding to each of the unique ionic species. The spectrum is a fingerprint of the parent compound. Libraries of these ion spectra remain resident in the IONSCAN software and are in the screening process.
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Kaye Validator® ITMS
The Kaye Validator® ITMS is a portable at-line instrument for accelerating the cleaning validation process. Operators can assess system cleanliness at-line with no delay, and get production lines up and running quickly. As an alternative to traditional analytical techniques, (HPLC and TOC) this instrument provides significant gains in production line utilization and capacity.
Features & Benefits:
Proprietary ion trap technology for unparalleled sensitivity - user programmable to pico-gram detection levels
Rapid sample analysis time (approximately 10 seconds)
Portable design for at-line use
Minimal operator training required
Low sample analysis cost
Self-calibrating
Rapid method development
Minimal consumable costs
Increased capacity utilization and productivity-by minimizing equipment downtime attributed to waiting for traditional analytical lab test results
Increased profitability-by effectively increasing installed capacity, and significantly reducing sample analysis cost
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Introducing the New LTQ XL™ Linear Ion Trap
The LTQ XL extends the MSn performance of the LTQ linear ion trap with powerful new tools to generate extensive structural information for the most demanding proteomics and metabolism applications.
* Multiple dissociation techniques (PQD, ETD, CID)
* Extensive coverage for predicted and unpredicted metabolites
* Fast polarity switching for high-sensitivity analysis of unknowns
* Intelligent Data DependentTM acquisition
* Platform for high resolution, accurate mass hybrids
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Performance and reliability for every budget
The Agilent 6300 Series Ion Trap LC/MS systems deliver robust, sensitive, data-dependent MS/MS analysis that makes structural confirmation and sample identification easier.
6310 – makes high performance and data-dependent MSn economical for every lab
6320 – provides greater sensitivity, mass resolution, and scan speed
6330 – offers ultimate sensitivity for low-abundance analytes
6340 – adds electron transfer dissociation (ETD) for better post translational modification (PTM) characterization and protein identification
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The 3200 Q TRAP® LC/MS/MS system provides excellent sensitivity, superior dynamic range, and reliability across a range of identification and quantitation applications. With features found in our industry-leading LC/MS/MS systems, the 3200 Q TRAP system brings true hybrid triple quadrupole/Linear Ion Trap capabilities within the reach of any lab.
- Patented hybrid triple quadrupole/Linear Ion Trap technology takes you farther than conventional ion traps and enables you to screen, identify, and quantitate in a single analysis.
- Easily interchangeable ion sources are available so you can perform a wide range of applications.
- This compact, easy to use system is rugged enough for continuous operation so you increase your productivity.
Move Beyond Conventional Ion Traps
Hybrid triple quadrupole/Linear Ion Trap technology provides increased sensitivity and enables you to move from screening to identification to quantitation in a single analysis. By combining triple quadrupole scanning functionality with sensitive linear ion trap scans, you can reduce analysis time and get more information from every experiment.
Versatile, Integrated System
The 3200 Q TRAP system meets multiple challenges because it is a powerful, easy to use, compact benchtop system that is rugged enough to allow for continuous high throughput operation. With intuitive, application-specific software and automation features it's easy to see why the 3200 Q TRAP system fits perfectly into the workflows of any drug discovery, proteomics, or forensics laboratory.
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Today, researchers have clear demands for LC/MSn:
Sensitivity and fast scan rates to extract more information from each HPLC peak.
Smart software tools to simplify data interpretation and management.
Streamlined workflow in times of ever- growing sample numbers and throughput.
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The 4800 Plus MALDI TOF/TOF™ Analyzer is the next generation of tandem time-of-flight MS/MS systems, providing the highest level of protein coverage, throughput, and confidence in quantitative proteomic analysis. The analyzer combines all of the advantages of MALDI in a flexible, easy-to-use, ultra-high-performance mass spectrometer with all the advanced capabilities of ProteinPilot™ v2.0 software.
- Ideal system for protein biomarker discovery, providing simultaneous identification and quantitation of up to 8 samples at a time (8-plex workflow) using iTRAQ™ Reagents.
- Fully supports LC MALDI workflows, allowing you to mass analyze without the time constraints of LC.
- Compatible with ProteinPilot v2.0 software for increased protein coverage and confidence in identification and quantitation results.
- OptiBeam™ on-axis laser provides ten times greater sensitivity to identify and quantitate low-abundance proteins in complex biological samples.
- High-resolution precursor ion selection, enabled by the QuanTIS™ precursor selector, lets you detect and identify peptides that other systems miss and makes it easier for you to interpret your data by simplifying MS/MS spectra.
- Simple experiment setup and fast mass analysis maximizes laboratory productivity.
- High-energy, information-rich fragmentation patterns unavailable on other instrument platforms enable you to analyze carbohydrates, lipids, and other biological components.
- Improved on-board computing capabilities handles large scale protein discovery studies with faster processing and automated data backup.
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The AXIMA series of MALDI TOF Mass Spectrometers
Drawing on the innovative technology developed by Kratos Analytical, the AXIMA series of MALDI TOF Mass spectrometers offers powerful performance for a diverse range of high throughput biochemical applications:
- Proteomics
- Combinatorial chemistry
- Micro-satellite DNA
- SNP analysis
All systems offer the INTELLIMARQUE™ functionality which allows fully-automated data-dependent PMF/PSD proteomics experiments.
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MALDI SYNAPT HDMS
A dual ionization mass spectrometer featuring MALDI and atmospheric pressure ionization. The system is operable in both time-of-flight (TOF) and ion-mobility/TOF modes.
Features:
- Triwave™ Technology, which provides access to the unique benefits of Ion Mobility Spectrometry (IMS)
- Time-aligned parallel (TAP) fragmentation for first- and second-generation fragmentation structural information in a single experiment
- Rapid, exchangeable MALDI/API sources
- High-duty cycle (HDC) mode for enhanced sensitivity over a wide mass range
- Integrates with the nanoACQUITY UPLC® System and the CTC PAL MALDI Spotter/Fraction Collector, so you can perform off-line nanoscale separations with minimized sample complexity and dynamic range issues
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The well-known Bruker Daltonics "FLEX" series stands for maximum performance and reliability, providing:
Superior performance characteristics
Maximum flexibility and scalability
Highly automated operation
Seamless interface with the biological lab due to MALDI targets in MTP (or MTP compatible) format
Proprietary AnchorChip™ MALDI target technology
Easy-to-use Compass software
Maximum up-time and comprehensive service concept
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Offering high performance without the high price, the ProLine and ProMaxion series of process mass spectrometers provide features and a level of performance associated with much more expensive mass spectrometer systems. The ProLine (bench-top, general purpose) and ProMaxion (weatherproof, hazardous area) are ideal for a wide range of process analytical applications from Pharmaceutical to heavy industrial and refining.
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Mass spectrometers
