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DAWN® HELEOS
18-angle light scattering detector for the measurement of absolute molecular weight, size, and conformation of macromolecules in solution. The DAWN® HELEOS%u2122 may be used in batch mode (off-line) or connected on-line to an HPLC/HPSEC/AFFF, etc.. The DAWN® HELEOS%u2122 utilizes a 50mW solid-state laser operating at 658 nm and also has on-board digital signal processing hardware for up to four external devices such as RI and/or UV detectors. Also contains an analog output from the 90° detector for interfacing to strip chart recorders. The DAWN® HELEOS%u2122 has a gorgeous 64,000 color LCD display, thermostatic control options, depolarization options, and the ability to interface to high temperature GPC systems like the PL210 and Waters Alliance 2000. On-board analog-to-digital conversion with Ethernet communication for data acquisition.
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Mithras, the extremely versatile multimode microplate reader from BERTHOLD TECHNOLOGIES offers you a wide variety of technologies as there are:
Luminescence
Absorbance
Fluorescence (top and bottom)
Fluorescence Polarisation (FP)
AlphaScreen
BRET
FRET
HTRF®
Time-resolved Fluorescence
The Mithras LB 940 operates with dedicated optical paths (DOPS) to ensure the best available performance for each technology.
The unit combines fluorescence and luminescence modes with the uncompromised performance of dedicated instruments. The sensitivity of the luminescence function exceeds even that of the best dedicated plate luminometers.
BRET and FRET for receptor studies and protein/protein interactions can also be measured with exceptional sensitivity as well as homogenous fluorescence polarization assays.
Mithras can be supplemented with up to 4 reagent injectors %u2013 based on the proven and highly precise JET technology %u2013 and a temperature control unit for the microplates. That offers extensive opportunities to the users to perform a huge number of applications including enzyme activities, phagocytosis, calcium flux, cell viability, apoptosis, protein and DNA determinations or protein-protein interactions.
The software is supporting a multitude of functions including standard curves and kinetic data reduction as well as the 21 CFK part 11 requirements.
For medium level throughput environments such as ´assay development´ or ´secondary screening´ the instrument can be equipped with a stacker.
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TriStar is the ideal instrument for biomedical research whenever multiple reading technologies and excellent performance are needed.
• Absorbance
• Luminescence
• Fluorescence
• BRET
• FRET
All common applications including DNA and protein quantification, Calcium monitoring, reporter gene assay, ATP determination, cell growth and viability, apoptosis, phagocytosis and enzyme kinetics will run on TriStar LB 941.
In addition, assays based on the reading technologies BRET, e.g. functional GPCR assays, and FRET for protein-protein interactions may be performed.
Up to 4 reagent injectors can be set up to dispense multiple activators or detection reagents at any time and with user-adjustable volumes during the measurement.
A temperature controlled microplate compartment (5°C above room temperature to 40°C) ensures stable conditions whenever temperature sensitive enzymes or cells are in use.
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Biomass Monitor 220
The Biomass Monitor 220 combines the latest advances in Radio Frequency dielectrics with intuative keypad control of settings and measurements. The Model 220 has an integral Multiplexer allowing up to 4 fermenters to be monitored. Advanced facilities are available with the Model 220 such as frequency scanning, polarisation correction and a multiple frequency system for aerated fermenters. The unique frequency scanning function on the Model 220 can allows changes in viability, cell size and metabolic activity of the cells to monitored
Areas of Use
The Biomass Monitor 220 can be used with all conventional bioreactors for the measurement of viable bacteria, yeast, animal, plant and other cellular biomass. Cells can be measured whilst in free suspension or immobilised on inert carriers such as glass beads and microcarriers. The system is ideal for research/pilot plants but full IOQ documentation can be provided for cGMP.
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The WyattQELS (Quasi-Elastic-Light-Scattering) instrument contains a real time digital correlator. The correlator measures the autocorrelation function of the intensity signal from any one angle of the DAWN or from the 90 degree location of the miniDAWN. The correlator then calculates the hydrodynamic radius at each elution time in order to provide hydrodynamic radii over an entire chromatographic peak.
Unlike many other dynamic light scattering instruments, the WyattQELS detector, when interfaced to the DAWN, allows one to measure correlation as a function of angle. Particles larger than 150nm may scatter relatively little light at 90 degrees because of intra-particle interface or "Mie scattering".
Features
Multiple Tau correlation design with a fixed range of channel from 480 nsec to ~1 hour (real-time).
No sample time optimization required!
A total of 264 channels with input data format of 5 bit for the first 16 channels, the the sample time doubles every 8 channels and the data width is incremented 1 bit for every set of channels. No pre-scaling required.
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Unique Proven Technology
> Reduce quarantine time
> The fastest response to contamination incidents
> Decrease inventory holding and warehouse costs significantly
> Rapid confirmation of corrective action effectiveness
> Minimize production disruption
> Decrease product losses
The CHEMUNEX Fluorescent Cell Labeling Technology (Fluorassure) has been widely used by the industry for more
than 15 years and is a well-established technology for the universal labeling of viable bacteria, yeasts and molds.
The ChemScan RDI® (Scan RDI® in the US) application using the fluorescent markers is approved by the FDA.
All and only viable microorganisms are labeled, even under conditions of stress such as the nutrient-depleted conditions of process water or in the presence of growth inhibitors, and are kept intact.
Chemunex technology provides direct labeling and detection, cell by cell. This provides results in microbial cell counts without the need of any calibration curve or interpretation.
3 analyzers are available for non filterable products: BactiFlow, BactiFlow ALS and D-Count
ScanRDI for non filterable products
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A step ahead: GANIMEDE-N with integrated digestion for nitrogen
determination.
After the successful launch of GANIMEDE-P, the new GANIMEDE-N analyser is the logical next step forward in LANGE laboratory automation.
The patented high-temperature module with flash cooling, which has already proved itself in the GANIMEDE-P, digests the samples in the shortest possible time.
The analysis method of the GANIMEDE-N corresponds to the requirements of DIN EN ISO 11905-1. With analysis thresholds of 0.5 and 200 mg/l, GANIMEDE-N covers a broad sample spectrum. The evaluation is carried out photometrically in the UV range. Up to 50 samples can be analysed in series. It takes only 5 minutes to analyse a single sample!
Time-consuming preparation of your own reagents is no longer necessary, as ready-to-use chemicals are also available for the GANIMEDE-N, ensuring that analytical convenience can go hand in hand with top quality.
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Biochrom Anthos 2020 Microplate Reader
The 2020 is a great value stand alone microplate reader with powerful customised software for routine absorbance assays in research, quality control and diagnostics. A reliable laboratory workhorse that can handle a wide range of microplate based assays eg ELISA.
- Single or dual wavelength measurements plus kinetic measurements
- 4 commonly used filters supplied as standard 405nm, 450nm, 492nm and 620nm.
8 position filter wheel -additional filters available
Language Choice English or German
Flexible plate layouts
Comprehensive analysis and curve fitting
Kinetic mode
Easy data export to a PC
ADAP Basis PC Software supplied as standard
Additional Options
-Upgrade to ADAP Expert PC software
-Reader Check plate for QC validation
-Additional filters
Special Offer!
For a limited period we are offering a free laser printer to connect with this microplate reader. Just add 80-5000-38 to your order, and you will receive a printer and cable to connect to your microplate reader completely FREE!
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Biochrom Asys Expert Plus Microplate Reader
The Expert Plus is a stand-alone, multi-channel, filter based absorbance reader designed for laboratories that need a fast, accurate plate reader to handle a large number of microplates e.g. ELISA screening. The compact design is particularly suitable for labs where bench space is an issue.
- Fast - Just 10 seconds for a 96 well plate including flat, round and V bottom.
- Common filters supplied as standard. A "UV" option is available.
- Powerful data processing capacity built in. Stores up to 120 different methods and 120 standard curves plus the results from up to 100 microplates.
- Automatic self test and calibration
- Optional link to a PC
- Optional QC plate/software for easy validation
Special Offer!
For a limited period we are offering a free laser printer to connect with this microplate reader. Just add 80-5000-38 to your order, and you will receive a printer and cable to connect to your microplate reader completely FREE!
See www.biochrom.co.uk for a video demonstration.
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Biochrom Anthos Multiread 400 Microplate Reader
The MultiRead 400 is a fast, front loading, reliable multi-channel microplate reader suitable for general research, high throughput laboratories, or for integration into automated platforms. Ideal for applications such as ELISA, cell based assays (apoptosis and cytotoxicity studies), microbiology and enzyme kinetics. Use as a stand-alone or connect to a PC.
- Fast, just 10 seconds for 96 well plate
- Wavelength range 400-800nm (up to 6 filters) with shaking.
- Versatile on-board software with qualitative, quantitative and kinetic functions, plus a variety of curve-fit methods (linear regression, parabolic, Cubic, point to point, spline and 4 parameter)
- Stores both methods and results
- Connect to PC software included
Special Offer!
For a limited period we are offering a free laser printer to connect with this microplate reader. Just add 80-5000-38 to your order, and you will receive an printer and cable to connect to your microplate reader completely FREE! See website for more details.
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MINIVAP - The Worldwide Standard Vapor Pressure Tester
MINIVAP VPS and VPSH are extremely versatile instruments for the automatic determination of the vapor pressure behavior of gasoline and gasoline oxygenated blends, live and dead crude oil, solvents and other chemical compounds. Both types VPS and VPSH are the world wide standard instruments that are used by all major refineries, oil and pipeline companies, independent laboratories and car manufacturers.
The US-EPA declared MINIVAP as the official reference instrument for the USA.
The new MINIVAP VPXpert is an ergonomical, fully automatic vapor pressure tester: Designed for significantly improved precision, reliability and performance the VPXpert exceeds current vapor pressure standards. The instruments portable and rugged design, the maintenance free piston drive and measuring cell, a large, durable display and the optional 12V car adaptor have been specifically designed to withstand heavy duty environment and to enable safe outdoor operation. The VPXpert incorporates a shaker for crude oil samples, automated sample rinsing and enhanced dual-USB-connectivity. The innovative Sampling Pro™ technology, a high quality valve design, minimizes the risk of cross contamination between different sample types.
MINIVAP VPXpert VAPOR PRESSURE TESTER COMPLIES WITH:
* ASTM D5191, D6377, D6378
* EN 13016 1+2
* IP 394, 409, 481
EXCELLENT CORRELATION TO:
* ASTM D323 (Wet Reid), D4953 (Dry Reid), D5188 (V/L-ratio), D5190, D5482
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Compact and self-contained instrument for precise vapor pressure measurement
Provides quick, accurate results of vapor pressure up to 1,000 kPa (145 psi) within a temperature range of 0°C (32°F) to 100°C (212°F). Backed by state-of-the-art technology and highest quality design, the HVP 972 increases test productivity with perfect repeatability and reproducibility. Calibration history and quality-check tracking assure complete results traceability and meet rigorous quality assurance requirements.
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Voltammetry instruments and polarographs are favorably priced and compact, yet great in their detection capabilities.
- With voltammetry you can analyze trace elements in water, environmental samples or ultrapure chemicals!
- With the Cyclic Voltammetric Stripping technique (CVS) the analysis of organic additives in plating baths can be carried out easily and accurately.
Convincing applications
1) Apart from the determination of the total concentration, voltammetry allows to distinguish the different oxidation stages of metal ions or differentiate between free and bound metal ions as well as to specify the biological availability of heavy metals. VA instrument can also be used in mobile laboratories for environmental analysis.
2) Not only metals but also various organic compounds can be determined by voltammetry, but also some special anions. The determination of environmentally relevant anions like cyanide, sulfide, nitrite or nitrate is particularly interesting.
Automation makes work easier, increases sample throughputs and provides more exact results. For example, the CVS determination of organic additives in the plating industry can be carried out manually, partly automated or fully automated using the 838 Advanced Sample Processor.
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Gravimetric system for the automatic study of water sorption behaviour of materials at ambient pressure.
Special Features
- Rapid changes in experimental conditions.
- Dual balance arrangement.
- Viewing of samples during experimentation.
- Ultra fast data storage for detailed kinetic analysis.
- High dynamic and long-term balance stability.
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