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The JASCO X-LC™ Series extreme high pressure liquid chromatography is designed to operate at pressures apparoaching 15,000 psi for either gradient or isocratic separations. X-LC provides researchers with a powerful tool to use small particle columns while providing efficiency and speed that was previously not possible in a commercial HPLC. All of this while retaining the ability to run traditional HPLC methods.
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Prominence UFLC
Ultra Fast Liquid Chromatograph
In Pursuit of Higher Speed and Uncompromised Separation
The goal of high-speed HPLC is to enhance the laboratory’s productivity. We believe that analytical data obtained from high-speed HPLC must be as reliable as the data from conventional HPLC. For example, resolution must be maintained at an excellent level in the case of 10,000 analytical runs by high-speed LC, retention time and area repeatability must be excellent for small volume sample injection, the need for replacement parts should be minimized, and the instrument must work stably.
We successfully achieved speed and separation performance levels that do not depend on high pressure, while simultaneously offering a high level of precision and expandability not available with previous fast LC systems.
The combination of Prominence UFLC and new reversed-phase columns achieves ten times higher speed compared to a conventional HPLC system. Furthermore, a high-speed sample injection mechanism significantly reduces total analytical cycle time. With this combination, Prominence UFLC offers three times higher resolution than conventional HPLC so that the possibility of analysis is increased for samples that are not sufficiently separated by conventional HPLC.
The high-precision solvent delivery unit and autosampler improve repeatability in small volume sample injections for high-speed LC, achieving and maintaining excellent repeatability during long endurance tests.
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Since 20 years HPLC systems from Shimadzu are well known as reliable, ease to use instruments for routine analysis providing excellent performance for various applications. The broad range of instruments is designed to exceed requirements from R&D laboratories as well as QA/QC labs, from micro up to preparative HPLC:
- Modular HPLC for maximum of flexibility LC-20A prominence series
- Compact HPLC for routine application LC-2010
- Preparative HPLC modules LC-8A
- Special system solutions - e.g. sample preparation for LC-NMR and LC-MS Co-Sense
- Ionchromatography systems - CDD-10Avp and PIA-1000
Data Processing
Beside integrators, different software packages are available for data acquisition, data processing and supporting FDA compliance requirements.
FDA and GLP/GMP requirements
Shimadzu offers support to meet requirements for work under GLP/GMP conditions as well as getting compliance to FDA 21 CFR Part 11 criteria's. Our software packages Class VP and Lab Solutions include audit trails functions for method, data and system operation, our software solution concept CLASS Agent offers support for database assisted handling of analytical data for the complete laboratory incl. electronic signatures and electronic records.
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Varian 940-LC Analytical to Prep HPLC
Scale Up to Superior Performance and Reliability
The Varian 940-LC high performance liquid chromatograph is a fully integrated, pre-configured and pre-tested system. A complete solution in a compact footprint, the automated Varian 940-LC meets all your analytical and preparative chromatography needs today, and into the future.
The Varian 940-LC delivers:
- High performance analytical HPLC
- Fast, easy scale-up to preparative HPLC
- Flexible configurations
- Unmatched concentration range
- Versatile detection
- Superb, practical injections and collections
- Simple, productivity-boosting software
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Surveyor Plus HPLC System
The Surveyor Plus family of HPLC instruments is specifically optimized for the most demanding HPLC and LC/MS applications. Short cycle times, high sample capacity, low flow rate performance, and patented LightPipeTM technology have been integrated into one complete system for high-throughput sample processing environments.
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Waters Corporation develops high performance, value-added, system-based products that improve laboratory effectiveness for pharmaceutical, life science, environmental, food and beverage, agriculture and industrial applications. Our system offerings come with the chemistries, software, and instrumentation required for specific applications, and all are backed by the company's global, certified, post-sales service and support organization. Waters is dedicated to assuring the quality of results while helping users meet regulatory compliance.
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LC/MS
LC/MS single quadrupole mass analyser product family including mass directed fraction collection using prep LC/MS and web enabled software.
- LCMS 2010A Advanved
- Mass directed purification
- PsiPort™ mass directed auto-purification software
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LC Mass Spectrometer: Ion Trap and Quadrupole
500-MS LC Ion Trap
By delivering excellent sensitivity over the entire mass range in full scan mode, and exceptional MS/MS and MSn capabilities, the Varian 500-MS quickly provides superior information for even the most complex sample matrices.
320-MS Triple Quadrupole
The Varian 320-MS provides femtogram sensitivity, a 2000 m/z mass range and a choice of chromatographic and ionization configurations to match your budget and your needs – all in less than 72 cm (28 inches) of linear bench space
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The new Thermo Scientific LTQ Orbitrap Discovery provides access to the breakthrough Orbitrap™ technology for a wide range of labs. The robust, powerful and cost-effective system is ideally suited for general proteomics and metabolism applications, offering a superior alternative to Q-TOF systems. Featuring high resolution and excellent accurate mass capabilities, this hybrid LC-MS system achieves high throughput label-free profiling for differential expression while the MSn capability makes the instrument ideal for small molecule characterization and structural elucidation. The LTQ Orbitrap Discovery is a highly sensitive system with up to 30K resolution power and an exceptional scan rate, enabling the separation of trace level, isobaric analytes.
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The JASCO Models UV-2075 and UV-2070 are the most compact, full featured UV/Visible detectors that have ever been offered.
Occupying only 15 cm of bench space the UV-2075/2070 have versatile capabilities to cover the most complex needs of the modern analytical laboratory.
To ensure the most sensitive and stable HPLC detection these detectors utilize a Czerny-Turner mount monochromator covering a wide wavelength range from 190 to 900 nm with deuterium and halogen lamps (Model UV-2070) and from 190 to 600 nm with deuterium lamp (Model UV-2075). The excellent optical characteristics and full programmability of the UV-2075/2070 combined in a compact package is truly a new benchmark in HPLC detection.
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HPLC Columns
Fast LC Columns
Pursuit XRs Ultra 2.8 and Pursuit UPS 2.4 are designed to offer faster analysis with existing LC and LC/MS systems. They allow chromatographers to analyze samples faster while achieving higher resolution and reducing the cost per analysis without the need for capital investment. Both columns provide:
Method Development Flexibility - lower backpressures allow flows and mobile phases to be tailored to meet your applications needs
Maximum value. High performance separations achieved without the need for a new ultra high pressure system
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LC/MS
LC/MS single quadrupole mass analyser product family including mass directed fraction collection using prep LC/MS and web enabled software.
- LCMS 2010A Advanved
- Mass directed purification
- PsiPort™ mass directed auto-purification software
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LC Mass Spectrometer: Ion Trap and Quadrupole
500-MS LC Ion Trap
By delivering excellent sensitivity over the entire mass range in full scan mode, and exceptional MS/MS and MSn capabilities, the Varian 500-MS quickly provides superior information for even the most complex sample matrices.
320-MS Triple Quadrupole
The Varian 320-MS provides femtogram sensitivity, a 2000 m/z mass range and a choice of chromatographic and ionization configurations to match your budget and your needs – all in less than 72 cm (28 inches) of linear bench space
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The new Thermo Scientific LTQ Orbitrap Discovery provides access to the breakthrough Orbitrap™ technology for a wide range of labs. The robust, powerful and cost-effective system is ideally suited for general proteomics and metabolism applications, offering a superior alternative to Q-TOF systems. Featuring high resolution and excellent accurate mass capabilities, this hybrid LC-MS system achieves high throughput label-free profiling for differential expression while the MSn capability makes the instrument ideal for small molecule characterization and structural elucidation. The LTQ Orbitrap Discovery is a highly sensitive system with up to 30K resolution power and an exceptional scan rate, enabling the separation of trace level, isobaric analytes.
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Flow-through monitoring of radiolabelled compounds separated by chromatographic techniques has been established as one of the most powerful tools for identification of chemical and biochemical metabolites.
BERTHOLD TECHNOLOGIES is a leading supplier in radioactivity flow - through detectors for many years and is pleased to introduce the new instrument “FlowStar”.
A new user-friendly touch screen, the automatic measuring cell recognition and the two integrated bipolar analogue inputs are only some of the new features in the FlowStar.
Of course the latest applications were also implemented consequently in the FlowStar. The functionality for GLP/GMP is improved so that the user can continuously supervise all relevant parameters for GLP/GMP by “keystroke”.
FlowStar can easily be integrated in available HPLC systems by using the analog output signals. For a PC based solution the versatile RadioStar control- and evaluation-software is provided. For implementing the FlowStar into other HPLC Systems a DLL interface is available.
The FlowStar radiochromatography detection system contains components for all alpha, beta, gamma and PET isotopes in drug metabolism, pharmacology, environmental and clinical applications. BERTHOLD TECHNOLOGIES provides a complete system for Radio HPLC application, including cells, splitters, mixers, pumps and software.
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