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General description :
Expanding the capabilities of ICP-MS
The ELAN® DRC-e ICP-MS is a perfect fit for laboratories needing superior performance and low maintenance at an outstanding price. The ELAN DRC-e uses Dynamic Reaction Cell™ (DRC™) technology to eliminate polyatomic interferences, while innovative Axial Field Technology provides increased speed and stability. The ELAN DRC-e instrument is the ideal choice for laboratories facing the challenges of throughput and detection limits found in today's environmental samples.
Worry-free operation in all types of matrices
The ELAN DRC-e uses the same robust HF-resistant sample introduction system used on the ELAN 9000 system for worry-free performance in virtually any matrix. To ensure minimal maintenance, the ELAN DRC-e includes quick-change cones that resist clogging and drift. Plus, the reaction cell in the ELAN DRC-e is maintenance-free, eliminating the need for time-consuming cell-maintenance procedures.
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The AXIMA series of MALDI TOF Mass Spectrometers
Drawing on the innovative technology developed by Kratos Analytical, the AXIMA series of MALDI TOF Mass spectrometers offers powerful performance for a diverse range of high throughput biochemical applications:
- Proteomics
- Combinatorial chemistry
- Micro-satellite DNA
- SNP analysis
All systems offer the INTELLIMARQUE™ functionality which allows fully-automated data-dependent PMF/PSD proteomics experiments.
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QMS 403 C Aëolos® - Quadrupole Mass Spectrometer
The QMS 403 Aëolos® quadrupole mass spectrometer is a new compact mass spectrometer with a heated capillary inlet system for routine analysis of gases and, in particular, volatile decomposition products of thermal analysis. This system has been optimized for coupling to differential scanning calorimeters, dilatometers and thermogravimetric analyzers.
The high temperature of the gas transfer system and the absence of pressure reduction orifices practically eliminate condensation of decomposition products during thermal analysis experiments. This achieves a high detection sensitivity and facilitates quantitative detection of all identified gas components.
Via the inlet system with the fused silica capillary, other gas sources can be investigated with the QMS 403 C Aëolos® independent of thermal analysis; for that purpose, the QMS is operated with the self-contained software.
The concept of the NETZSCH thermal analysis instruments has been laid out from the start for coupling with gas analysis systems like the QMS 403 C Aëolos® or an FTIR system with a gas cell, through consistent optimization of the gas paths with complete heating from the furnace to the gas detector. This eliminates gas loss through condensation at cold spots and only very low carrier gas flows are sufficient for complete transfer.
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Since the introduction of the first Shimadzu Quadrupole GCMS system in 1972 Shimadzu has continuously improved its GCMS products. The current products range from the easy EI system for routine analysis purposes to the highly sensitive and flexible system GCMS-QP2010 which offers all possibilities for even the most advanced applications.
Shimadzu´s GCMS systems
QP2010 Plus: GCMS analysis for the highest demands and all application needs: ultimate sensitivity with highest flexibility
Autosamplers:
- AOC-20i Autoinjector
- AOC-20s Autosampler tray for up to 150 samples
- AOC-5000 Automatic injection system
Pyrolyzer:
- Py-2020iD from Frontier Lab
LabSolutions Software Series:
GCMSsolution the new up-to-date software for GCMS analysis. Comprehensive QA/QC functions make working in a GLP/GMP environment easy. Part of the Labsolutions software series for chromatography
CLASS Agent:
Data Management software with comprehensive support for FDA requirements
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Quadrupole ICP-MS
Thermo Scientific XSERIES 2 ICP-MS - The Thermo Scientific XSERIES 2 ICP-MS with advanced H2/He collision cell technology, licensed from Battelle, provides uncompromised multielement analysis for all elements including Ca, Fe, As and Se – and represents the most comprehensive quadrupole ICP-MS platform for high performance across the entire periodic table. Alongside proven high matrix tolerance, the XSERIES 2 operates with 10x less background noise than the nearest competitor – ensuring results of the highest analytical quality.
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Introducing the 810/820-MS
Inductively Coupled Plasma-Mass Spectrometers (ICP-MS)
Varian, Inc. continues to find new and novel ways to meet your changing needs. When you buy a Varian ICP-MS, you’re buying more than just an instrument. You’re buying a relationship with one of the most respected and experienced instrument companies in the world.
If you've ever wished that ICP-MS could be simpler, wish no
more. The Varian 810-MS and 820-MS make ICP-MS effortless.
No matter what your requirements, with a Varian ICP-MS,
you can tackle any application with ease.
Varian 820-MS
In addition to all the features of the 810-MS, the 820-MS features Varian's unique collision reaction interface (CRI)* system, which provides simple, routine removal of troublesome spectroscopic interferences. The result is faster, more flexible interference-free analysis without the worry of complex multipole or scanning quadrupole ion guides or cells. And, by coupling autotuning of all instrument parameters, including CRI gases, instrument productivity is greatly enhanced.
Varian 810-MS
The Varian 810-MS delivers high sample throughput and the ultimate in analytical performance. Core to this instrument is Varian's patented high-efficiency 90 degree ion optics and double off-axis quadrupoles, which deliver exceptionally low background noise and unmatched sensitivity - at more than 1 million counts per second for 1 microgram/liter.
For samples that don't require CRI, the Varian 810-MS
is an ideal instrument with industry leading sensitivity for
trace and major elemental analysis.
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From routine applications to cutting edge research, the Agilent 7500 Series is task-ready. Since the introduction of the world's first Benchtop ICP-MS in 1994, Agilent has led the way in important ICP-MS innovations making the 7500 Series the current state of the art in ICP-MS. The 7500 Series delivers the highest levels of performance for trace metals analysis, while retaining ease of use, flexibility and reliability through automation and excellence in design. Furthermore, our great products are backed by a large team of support specialists - on-hand to help you get the most from your instrument.
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Introducing the New LTQ XL™ Linear Ion Trap
The LTQ XL extends the MSn performance of the LTQ linear ion trap with powerful new tools to generate extensive structural information for the most demanding proteomics and metabolism applications.
* Multiple dissociation techniques (PQD, ETD, CID)
* Extensive coverage for predicted and unpredicted metabolites
* Fast polarity switching for high-sensitivity analysis of unknowns
* Intelligent Data DependentTM acquisition
* Platform for high resolution, accurate mass hybrids
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Offering high performance without the high price, the ProLine and ProMaxion series of process mass spectrometers provide features and a level of performance associated with much more expensive mass spectrometer systems. The ProLine (bench-top, general purpose) and ProMaxion (weatherproof, hazardous area) are ideal for a wide range of process analytical applications from Pharmaceutical to heavy industrial and refining.
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Thermo Scientific TSQ Quantum triple quadrupole system is the only instrument that enables Highly Selective Reaction Monitoring (H-SRM) performance allowing you to analyze complex samples quickly and efficiently. HyperQuad quadrupoles yield higher ion transmission, minimizing false positives and maximizing sensitivity.
TSQ Quantum Access - Unsurpassed Price to Performance
The TSQ Quantum Access offers versatility with its best in class mass range (m/z 30- 3000), QED-MS/MS structural quantification scan mode, and H-SRM capability. With the ability to scan for more than 300 analytes in a single experiment and with fast positive/negative mode switching, the TSQ Quantum Access enables routine multi-residue screening. The common ion path and ion source shared by the TSQ Quantum product line allows for easy method transfer between the different platforms, a significant advantage in today's business environment.
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Triple-Quadrupole Mass Spectrometer Enhances Sensitivity in LC/MS -- Novel API Interface and Ion Optics Improve Performance
Redefining Benchtop LC/MS/MS
THe Varian 325-MS is a robust, reliable option for many applications, including environmental, food-safety, clinical research, and forensics. Designed to handle difficult small-molecule analyses, it offers a choice of ionization modes and scanning techniques to ensure you find the information you are looking for. The Varian 325-MS innovative technologies facilitate increased productivity in a high-throughput environment.
The Varian 325-MS Provides:
Accurate and reproducible results in difficult matrices
Highest sensitivity amongst comparable triple-quadrupole instruments (500 femtograms reserpine)
Easy-to-use vESI interface
Increased number of target analytes possible in multi-residue methods
Reduced need for front-end maintenance
It features a "vortex" API interface (vESI; petent pending) and "Gold-Guard" (patent pending) ion-optics that jointly enhance sensitivity, ruggedness and throughput. The higher sensitivity means you can analyze more compounds in a single run. The more rugged design means less downtime for cleaning the source. That adds up to an extremely productive solution.
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Long accepted as a tool for depth profiling thin films and insulating materials, Quadrupole Dynamic SIMS (D-SIMS) has become the surface analysis method of choice for characterizing ultra shallow implants used in semiconductor devices. Shrinking device geometries require ultra-shallow, high dose implantation of intentional dopants such as boron and arsenic and the use of thinner, highly controlled insulating layers (oxides and oxynitrides). These critical processes of modern semiconductor device fabrication are ideally suited to the analytical performance of Physical Electronics' ADEPT-1010 surface analysis instrument.
The ADEPT-1010 dynamic SIMS analysis instrument employs a unique secondary ion extraction system which provides high transmission with a quadrupole dynamic SIMS platform. High transmission yields low detection limits offering routine analyses of implant junction depth and dose. These critical factors in implantation can be measured with reproducibility of a few percent, consistent with the needs of the semiconductor industry. In addition, the ADEPT-1010 surface analysis instrument can be used to monitor the nitrogen content of nitrided oxides with thickness of 5nm and less.
The ultra-high vacuum environment of the ADEPT-1010 allows for depth profiling of low levels of oxygen and carbon in SiGe layers while maintaining excellent depth resolution and low sputter rates. This capability is important to the integrity of these high speed SiGe devices.
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The new PHI TRIFT V nanoTOF surface analysis instrument is the next generation of PHI’s highly successful line of TOF-SIMS instruments which utilize the patented TRIFT analyzer. Several significant improvements have been introduced with the nanoTOF. The superior performance TRIFT analyzer has been combined with a revolutionary new sample handling platform. This innovative new sample handling platform was designed from the ground up specifically for TOF-SIMS, adding the flexibility needed to accommodate samples with complex geometries. In addition, improvements have been made in charge compensation and ion gun performance.
Time-of-Flight Secondary Ion Mass Spectrometry (TOF-SIMS) provides sub-micron elemental, chemical, and molecular characterization and imaging of solid surfaces and thin films for products such as semiconductors, hard disk drives, polymers, paint and other surface coatings. Manufacturing companies in the chemical, semiconductor and pharmaceutical industries can use the nanoTOF to improve product performance, conduct failure analysis and manage process control. Time-of-Flight SIMS surface analysis instruments differ from Dynamic SIMS instruments in that they can analyze the outermost one or two mono-layers of a sample while preserving molecular information.
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Innovative MALDI-TOF and TOF/TOF technology for reliable and detailed protein characterization, high resolution MALDI imaging and validated biomarker discovery. Patented smartbeam™ laser technology is a must for MALDI Molecular Imaging and gives access to superior performance in any Proteomics project.
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TwinMS
The TwinMS has two V&F IMR mass spectrometers built-in that can be operated in parallel or series depending on the application requirements. High speed trace emission analysis is the foundation for all V&F mass spectrometers. The added features of the TwinMS allows for simultaneous measurement of pre- and post catalyst and ultra high speed reaction measurement capabilities. These added features can help trim overall R&D costs by reducing expensive test cell time.
Instrument operation is based on quadrupole mass spectrometry with IMR technology. This combination allows for unrivalled performance in sensitivity, speed, selectivity and robust and reliable operation in industrial use.
Attributes:
Ultra-fast, multi-component analysis in ppm and ppb area
Two mode operation
2 gas channels can be measured simultaneously for real time analysis of up to 6 compounds per channel
Fast switching between 2 gas channels with fast measurement of up to 20 components on the 2 parallel operated mass spectrometers
Simultaneous pre- and post catalyst capabilities provides substantial cost savings through reduced test cell runs
Excellent response and reproducibility
Typical detection limit in the ppb area
3 to 4 decades dynamic range
Low operating costs
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Superior Q-TOF performance for greater analytical confidence
Using proprietary True Hi-Def TOF technology, Agilent’s 6520 and 6530 bring an unrivaled combination of mass accuracy and resolution, sensitivity, acquisition speed, and in-spectrum dynamic range to your toughest research challenges. The new Agilent 6530 Accurate-Mass Q-TOF LC/MS with Agilent Jet Stream thermal gradient focusing technology increases sensitivity by a further 5X for even greater analytical confidence. All 6500 Series instruments feature the powerful, compound-centric MassHunter Workstation software with its unsurpassed data mining and qualitative and quantitative data analysis capabilities.
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The micrOTOF™ provides powerful exact mass measurements in an easy-to-use benchtop package. Featuring excellent mass resolution and mass accuracy in combination with true isotopic pattern, micrOTOF is the perfect choice for straight-forward formula determination of small molecules, quality control of intact proteins, and metabolic studies.
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FTMS Flexibility and Performance for the Most Challenging Problems
FTMS is synonymous with performance. The apex-ultra combines the power of FTMS with the latest quadrupole technology (complete with linear ion trapping modes) and superb multipole collision cell for a quantum leap in analytical capability. The unique geometry provides facile and efficient precursor mass selection with collision induced dissociation in the Qh "front end" to the FTMS for on-the-fly LC-MS/FTMS analysis. Moreover, the Qh “front end” to the FTMS provides the added functionality for the enrichment of low abundant species via mass selective accumulation.
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Kaye Validator® ITMS
The Kaye Validator® ITMS is a portable at-line instrument for accelerating the cleaning validation process. Operators can assess system cleanliness at-line with no delay, and get production lines up and running quickly. As an alternative to traditional analytical techniques, (HPLC and TOC) this instrument provides significant gains in production line utilization and capacity.
Features & Benefits:
Proprietary ion trap technology for unparalleled sensitivity - user programmable to pico-gram detection levels
Rapid sample analysis time (approximately 10 seconds)
Portable design for at-line use
Minimal operator training required
Low sample analysis cost
Self-calibrating
Rapid method development
Minimal consumable costs
Increased capacity utilization and productivity-by minimizing equipment downtime attributed to waiting for traditional analytical lab test results
Increased profitability-by effectively increasing installed capacity, and significantly reducing sample analysis cost
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Performance and reliability for every budget
The Agilent 6300 Series Ion Trap LC/MS systems deliver robust, sensitive, data-dependent MS/MS analysis that makes structural confirmation and sample identification easier.
6310 – makes high performance and data-dependent MSn economical for every lab
6320 – provides greater sensitivity, mass resolution, and scan speed
6330 – offers ultimate sensitivity for low-abundance analytes
6340 – adds electron transfer dissociation (ETD) for better post translational modification (PTM) characterization and protein identification
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The 3200 Q TRAP® LC/MS/MS system provides excellent sensitivity, superior dynamic range, and reliability across a range of identification and quantitation applications. With features found in our industry-leading LC/MS/MS systems, the 3200 Q TRAP system brings true hybrid triple quadrupole/Linear Ion Trap capabilities within the reach of any lab.
- Patented hybrid triple quadrupole/Linear Ion Trap technology takes you farther than conventional ion traps and enables you to screen, identify, and quantitate in a single analysis.
- Easily interchangeable ion sources are available so you can perform a wide range of applications.
- This compact, easy to use system is rugged enough for continuous operation so you increase your productivity.
Move Beyond Conventional Ion Traps
Hybrid triple quadrupole/Linear Ion Trap technology provides increased sensitivity and enables you to move from screening to identification to quantitation in a single analysis. By combining triple quadrupole scanning functionality with sensitive linear ion trap scans, you can reduce analysis time and get more information from every experiment.
Versatile, Integrated System
The 3200 Q TRAP system meets multiple challenges because it is a powerful, easy to use, compact benchtop system that is rugged enough to allow for continuous high throughput operation. With intuitive, application-specific software and automation features it's easy to see why the 3200 Q TRAP system fits perfectly into the workflows of any drug discovery, proteomics, or forensics laboratory.
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Today, researchers have clear demands for LC/MSn:
Sensitivity and fast scan rates to extract more information from each HPLC peak.
Smart software tools to simplify data interpretation and management.
Streamlined workflow in times of ever- growing sample numbers and throughput.
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The 4800 Plus MALDI TOF/TOF™ Analyzer is the next generation of tandem time-of-flight MS/MS systems, providing the highest level of protein coverage, throughput, and confidence in quantitative proteomic analysis. The analyzer combines all of the advantages of MALDI in a flexible, easy-to-use, ultra-high-performance mass spectrometer with all the advanced capabilities of ProteinPilot™ v2.0 software.
- Ideal system for protein biomarker discovery, providing simultaneous identification and quantitation of up to 8 samples at a time (8-plex workflow) using iTRAQ™ Reagents.
- Fully supports LC MALDI workflows, allowing you to mass analyze without the time constraints of LC.
- Compatible with ProteinPilot v2.0 software for increased protein coverage and confidence in identification and quantitation results.
- OptiBeam™ on-axis laser provides ten times greater sensitivity to identify and quantitate low-abundance proteins in complex biological samples.
- High-resolution precursor ion selection, enabled by the QuanTIS™ precursor selector, lets you detect and identify peptides that other systems miss and makes it easier for you to interpret your data by simplifying MS/MS spectra.
- Simple experiment setup and fast mass analysis maximizes laboratory productivity.
- High-energy, information-rich fragmentation patterns unavailable on other instrument platforms enable you to analyze carbohydrates, lipids, and other biological components.
- Improved on-board computing capabilities handles large scale protein discovery studies with faster processing and automated data backup.
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The well-known Bruker Daltonics "FLEX" series stands for maximum performance and reliability, providing:
Superior performance characteristics
Maximum flexibility and scalability
Highly automated operation
Seamless interface with the biological lab due to MALDI targets in MTP (or MTP compatible) format
Proprietary AnchorChip™ MALDI target technology
Easy-to-use Compass software
Maximum up-time and comprehensive service concept
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The Thermo Scientific Prima dB process mass spectrometer provides fast, precise analysis for improved process control and features a fault-tolerant design that maximizes uptime. Based on more than 15 years of proven magnetic sector technology, it has set new standards for performance and reliability. The powerful, intuitive Thermo Scientific GasWorks software suite simplifies initial setup of the Prima dB and enables the use of a remote computer which can then display process measurement and diagnostic data, or it can be unplugged leaving the Prima dB to operate in full stand-alone mode. A variety of sample inlet systems are available depending upon the process being monitored with multi-port inlets available where an atmospheric pressure process requires more than one sample port. The analyzer is a fast, highly stable scanning magnetic sector mass spectrometer that generates a high-energy ion beam from the sample gas. This ion beam is separated into its constituent molecular fragments by the electromagnet and the signal intensity is measured by the auto-zeroing amplifier. A series of distributed microcontrollers provide complete automatic control of the process without requiring any manual interventions. Data communication is provided by a series of fully redundant gateways that can be independently configured for optimum communication with the DCS or SCADA system. Many data highway protocols can be supported by use of an integral protocol converter and discrete contacts, or analog signals can be connected to PLCs for various control purposes. In addition, the Prima dB features an ergonomic design for ease of maintenance and is supported by the industry’s best warranty.
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Airsense EI (Compact)
Synchronized Double Mass Spectrometer
A complete gas analysis package designed to provide the customer with all-in -one analysis capabilities and to eliminate the cost and need for racks of multiple individual emission monitors
The Airsense Compact is a double mass spectrometer featuring the molecule Reaction (IMR) Mass Spec coupled with a Electron Pulse Ionization (EIMS) Mass Spec principle. Along with the vast number of trace components analysis capabilities of the Airsense MS, is the added capabilities of bulk gas analysis for N2, He, H2, CO2, and Ar at the same time.
Features include:
- High speed multi-component analysis, high selectivity, high flexibility
- On-line monitoring of raw bulk gas along with trace analysis
- High speed, rugged, and cost effective, eliminating the need for wide number of rack monitors
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MKS Mass Spectrometry gas analyzer products are innovative in-situ process monitoring instruments that are fully integrated, application-specific packages, including component residual gas analyzers (RGAs), web-enabled RGA's, analytical equipment, and process RGAs and control software.
Vacuum Monitoring and e-Diagnostics
- Ultra High Vacuum (UHV)
- CVD Processes
- Vacuum Baseline RGA
- Ion Implant
- Photoresist Detection
- High-Pressure RGA
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Pfeiffer Vacuum supplies a broad portfolio of mass spectrometers, ranging all the way to high-perfomance mass spectrometers for plasma analysis.
A mass spectrometer can be used to analyze the composition of a gas mixture in a production system. Because in production processes it is not only important to know "how much" is contained in the mixture, but also "what" it is that is contained in it.
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Agilent 6100 Series Quadrupole LC/MS systems put the sensitivity, selectivity, and information content of mass spectrometry into an amazingly compact package. Four models are available:
6110 - An economical entry to the power of LC/MS
6120 - The added productivity of ion polarity switching
6130 - A research-grade LC/MS with outstanding sensitivity
6140 - Maximum performance plus fast scanning for fast chromatography and high-throughput applications
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The AB SCIEX Triple Quad™ 5500 system is today’s most sensitive triple quadrupole mass spectrometer that is designed to deliver high levels of sensitivity and robustness for even the most complex and demanding matrices. The AB SCIEX Triple Quad™ 5500 exceeds the performance required by even the most demanding DMPK and ADMET studies and excels at multi-component quantitation required by environmental, targeted quantitative proteomics, clinical research, and food and beverage applications. Built from the ground up on new, fast eQ™ electronics, the system combines new and improved patented technologies with the powerful Analyst® software.
- Robust, high-throughput platform for all stages of pharmaceutical development.
- Excel at highly multiplexed peptide quantitation
- Unequalled accuracy and precision for quantitative analysis.
- Smaller footprint
- Lowest limits of detection available for DMPK and ADMET studies.
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