Atomic force microscope (AFM) for use in air or liquid MFP-3D-BIO™
Asylum Research
The MFP-3D-BIO™ is the only full-capability AFM on an inverted optical microscope. It provides the highest sensitivity and most accurate images and measurements possible on an inverted optical platform. The NPS™ closed loop nanopositioning sensors on all three axes ensure distortion-free images on samples as small as proteins and as large as cells - in both air and liquid. The MFP-3D-BIO measures the cantilever deflection to better than 20pm (8pm typical) without artifacts, making the it ideal for force measurements such as unfolding single molecules or probing cell mechanics. Asylum's superior sensor and flexure stage technology coupled with our intuitive control software also gives you the ability to zoom and offset with a single mouse click - even from a previously captured image. Independent lateral (X-Y) and vertical (Z) positioning stages eliminate the crosstalk errors common to systems using tip-scanners. The large Z range (up to 40µm) enables imaging of tall samples and cells, force curves on highly adhesive soft materials like gels, and other challenging applications. All standard AFM scanning modes are supported, including contact mode with lateral force, AC mode with phase, and advanced modes such as Dual AC™, nanomanipulation, nanoindentation and more. High numerical aperture, water immersion, and TIRF objectives are all accommodated. No other AFM can match the MFP-3D's performance for optical integration, high resolution imaging, quantitative force measurements, and environmental controls.
