Keofitt sampling valves allow quick sampling from any vessel. They have very few moving parts and are quickly cleaned or sterilized between samplings to prevent residual build up. The inner radial diaphragm seal can be changed to prevent any cross-contamination. Sterile samples can also be taken with the sample bottle assembly. These valves were first designed to be used in fermentation vessels. Due to their simple operation and solid performance, Keofitt valves can now be found in all phases of the process stream. Different body styles are available to accommodate most horizontal access.