Fluorescence lifetime imaging microscope
Vectra™ Caliper

Vectra’s automated, high-throughput imaging capabilities make it the most advanced system available for extracting proteomic and morphometric information from intact tissue sections. Combining three key components - automated slide-handling, multispectral imaging technology and pattern recognition-based image analysis – the system is a powerful tool for today’s pre-and clinical studies. Vectra is well suited for automated applications in:

Tissue biomarker discovery and validation
Signaling pathway analysis in cancer research and drug development
Microenvironment analysis, including assessment of tumor immunogenicity
Tissue cytometry, including multiplexed per-cell measures of nuclear, cytoplasmic, and membranous protein expression

The system accurately measures protein expressions and morphometric characteristics on whole slides or in distinct tissue regions of interest. Imaged tissue sections can be labeled with immunofluorescent (IF) or immunohistochemical (IHC) stains, or with conventional stains such as H&E and trichrome. When using IF or IHC stains, one or multiple proteins can be measured on a per tissue, per cell, or per cell compartment (e.g. nuclear, cytoplasmic) basis - even when signals are spectrally similar, in the same cell compartment or obscured by autofluorescence.