Karl Fischer oven
FDA 21CFR Part11
Mitsubishi Chemical Analytech
Auto sample changer (33 samples) enforce customer's operation in quality control efficiently.
FDA21CFR P11 software option can be used in Pharmaceutical.
The moisture vaporization method is used to measure samples of solids that cannot be dissolved in dehydrated solvents or electrolytes, or samples that include interfering substances. The moisture content is vaporized by heating the sample in a flow of dried nitrogen gas. It is then captured in a dehydrated solvent or electrolyte and subjected to Karl Fischer titration.
Either coulometric or volumetric titration is used.
This method is commonly used with natural substances, such as minerals and rocks, and with macromolecules such as polymers and rubber. New areas of use include electronic materials, including printed circuit boards and wafers, and printing materials, such as toners. This method is also useful for petroleum products containing additives, such as lubricants.
Convenient moisture vaporization systems are available commercially to suit various purposes. They can be connected to either volumetric or coulometric titration systems and used to measure moisture content.
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