The Cascade II:512 broke new ground as the first EMCCD microscopy camera in the world to offer -80°C cooling without using water or liquid nitrogen. By eliminating the need for a bulky chilled-water circulator or cryogenic compressor, both of which are prone to leaks, blockages, and condensation, the Cascade II:512 affords maximum, long-term convenience. Deep cooling delivers ultrahigh gain and extremely low dark noise performance, enabling the 16-bit, high-resolution camera to satisfy even the most demanding sensitivity requirements. Key Features - 512 x 512 imaging pixels - 16 x 16-µm pixels - >92% quantum efficiency - Detector thermoelectrically cooled to -80°C - EM gain - Multiple-speed operation (10, 5, or 1 MHz) - Back-illuminated, frame-transfer EMCCD - Lifetime vacuum guarantee - 100% duty cycle - 16-bit images - Dual readout modes permit superb low-noise slow-scan readout as well as high-speed EMCCD operation