Laboratory electrophoresis unit
Wyatt Technology

(SANTA BARBARA, CALIFORNIA - March 1, 2010) - Wyatt Technology Corporation, the world leader in absolute macromolecular characterization instrumentation and software, announces the launch of its Möbiuζ™ (Mobius) mobility instrument. The instrument incorporates several patent-pending innovations to realize fast and reliable measurements of macromolecular electrophoretic mobilities. Besides being capable of swiftly measuring mobilities of large particles such as liposomes and VLPs, Wyatt Technology's Möbiuζ™ (Mobius) is the only laser-based instrument that achieves reproducible measurements of traditionally very challenging protein samples including antibody formulations, bovine serum albumin and lysozyme. It is designed specifically to address the unique measurement of protein mobilities rather than a remake of a device designed to measure particulates.
Electrical charge is a fundamental property of all macromolecules. In colloidal suspensions, the amount of charge and screening developed at the interfaces between particles and media is of utmost importance in determining the formulation stability. For many biomolecules such as proteins, electrostatic interactions also exercise a profound influence on their conformations and functions. Since a direct measurement of the interfacial potential is rarely feasible, the electrophoretic mobility has become the most popular and widely accepted proxy for molecular charge.