Biochemistry analyzer for glutamate, glutamine, glucose, lactate
YSI Life Science
For processes that require frequent monitoring and regulation, on-line analysis allows you the freedom to sample automatically and adjust both nutrient and byproduct concentrations.
Couple the YSI 2730 Aseptic Monitoring & Control system with the 2700 SELECT and pull samples directly from a bioreactor, measure important nutrients and byproducts, and immediately control the replenishment of nutrients, if needed, while maintaining the sterility of the process. All system components are sterilizable.
How On-Line Monitoring Works
The YSI 2730 Monitoring and Control system pulls sample directly from a bioreactor and pumps it to the YSI 2700 SELECT at programmed intervals. After each analysis, an antiseptic reagent, typically a dilute hypochlorite or hydroxide solution, is flushed through the sample lines and remains there until the next cycle to assure sterility.
For those bioprocesses in which loss of cells is a concern, you can connect the YSI system to an on-line filtration device. You can adjust system parameters, such as flow rate, to accommodate the needs of the filtration device.
For regulation, connect the YSI 2700 SELECT to a feed pump. When nutrient concentration falls below a programmed setpoint, the YSI 2700 SELECT will signal the feed pump to add nutrient to the bioreactor.
Other system variables, such as sampling interval and concentration setpoint, allow you to customize the instrument for your process needs. For example, with processes that consume glucose quickly, you can configure the system to monitor glucose every few minutes. For other processes that consume nutrients slowly, monitoring every 30 or 60 minutes may be more appropriate.
