The gap between LC-separation and MALDI-TOF analysis is securely bridged with our spotOn system for target preparation and fraction collection. With guided control from vial to target spot, intuitive workflows, and full visibility into both separation and preparation, potentially complex bottom-up and top- down analyses of biologicals are met with confidence and ease.
LC sample spotting with accuracy and ease
Complex biological samples, including industrially-produced biopharmaceutical products, often require chromatographic separation for in-depth analysis, as they include a very wide and dynamic range of components. Structural features critical to therapeutic function may represent only a small percentage of the total protein content, and even small impurities may necessitate immediate action within a production scheme. The hardware and software components of our spotOn system are designed to support, accelerate, and improve these analytical workflows, saving time and money and enabling a more comprehensive insight into these valuable biologicals.
Fitting conveniently on the benchtop, the spotOn makes target preparation for LC-MALDI workflows faster and easier, promoting optimal MALDI matrix crystallization with all sample fractions for improved data quality and accelerate data collection. Predefined methods and detailed queries for all spotOn necessities, including MALDI targets and matrix solutions, reduce experimental error and promote high reproducibility from run to run, regardless of operator experience.