silica HPLC column / polymer
Pentafluoro reversed-phase column for unique selectivity
The PRP-h5 derives its hydrophobic functionality from a pentafluorinated polymer bead, delivering a selectivity difference from standard silica C18 stationary phases. This gives chromatographers the desired retention characteristics necessary for certain sample types. This difference is especially pronounced for halogenated solutes.
Unlike silica-based C8 or C18 columns, PRP-h5 has no stationary phase coating. Since there is no stationary phase to hydrolyze, the column maintains its performance characteristics longer than silica-based C8 or C18 columns.
Application Examples: Organic compounds: macromolecules (> 2,000 mw), pharmaceuticals, protein digests, tryptic digests, proteomics