MT-1000 / MT-1078 X-Y Translator System for Fixed-Stage Upright Microscopes The MT-1000/MT-1078 is a microscope translator, fixed-stage and manipulator platform for moving optical pathway electrophysiology. Two general styles are available. In the classic design (MT-1000), an independent stand is used for each manipulator and a similar stand holds the tissue chamber. A new style (MT-1078) uses a single large, fixed stage that is used for multiple manipulators and for the sample as well. MT-1000: the classic modular design features free-standing columns that provide rock solid mounting for the tissue recording chamber (MT-150) and multiple micromanipulators (MT-75). The columns are positioned around a movable table that provides X-Y translation of the optical pathway in order to view multiple locations within the chamber at high resolution. Many prefer this methodology as it maximizes working room for adjusting the microscope and changing pipettes. Furthermore, the independent stand design minimizes movement-related cross talk between manipulators. In the new MT-1078 translator system, the large fixed stage MT-78-FS is employed. In this design, it is easy to add additional manipulators and other devices to expand a setup as the manipulator/chamber support is a single large platform. Furthermore, an available magnetic stainless steel insert holds the chamber and allows the easy positioning of magnetically attached small devices nearby.