The ANDRITZ high-gradient magnetic separator allows the extraction of one protein fraction directly from the non-purified complex feedstock. With HGMS technology, the efforts of downstream processing can be decreased drastically while the yield is increased.
Strengths/benefits/features
High specific and selective protein harvesting
Separation efficiency of target protein up to 95% (depending on reaction time and magnetic particle concentration)
Replacement of purification steps, cell separation and chromatographic fractionation
Extreme reduction of separation time down to several minutes
Increased yield with less effort
Reduced down streaming efforts to reach final pureness
Research was conducted on the magnetic beads, the selective binding, and the elution process. The first rotor-stator magnetic separator systems were built in order to evaluate the separation principle. The separation, particle life time as well as elution processes were evaluated and proven