Flash chromatography column

silicaalumina

Overview
Prepacked columns with your preferred media. Scale purification with confidence: Biotage columns (Flash 75 / Flash 150 M/L / Flash 400 M/L, up to FL400L ~40 kg) can be prepacked with silica, alumina, ion-exchange media, scavengers or customer-specified sorbents to maintain method continuity from development to large-scale purification—fast, safe and reproducible.

Benefits

• Simplify flash chromatography scale-up by using the same chromatography media from development through larger-scale purification.
• Reduce variability with precisely prepacked columns, supporting reproducible and lower-risk scale-up workflows.
• Compatible with multiple media types to preserve method continuity and minimize manual handling or method changes during process optimization.

Key specifications

• Formats: Flash 75; Flash 150 (M/L); Flash 400 (M/L)
• Scale path: from ~5 g (development) → up to 40 kg columns (FL400L)
• Packable media: silica, alumina, ion exchange media, scavengers or customer-specified media if feasible

Use cases

• Lab-to-pilot and manufacturing chromatography for small molecules, peptides, lipids, linkers and high-potency API workflows where safety and reproducibility at scale are critical.

How it works

• 1. Prequalification: Feasibility discussion to define your media, purification goals, target scale and required column format.
• 2. Proposal: Recommended column configuration with a proposal covering setup, commercial terms and, if appropriate, a proof-of-concept evaluation.
• 3. Delivery: Receive ready-to-use prepacked columns plus documentation packages to support internal qualification and scale-up activities.

Technical specifications

• Product family: Configurable scale-up columns
• Models / formats: Flash 75; Flash 150 (M/L); Flash 400 (M/L)
• Scale range: from ~5 g (development) up to 40 kg columns (FL400L)
• Packable media: silica, alumina, ion exchange, scavengers, or customer-specified media if feasible
• Intended applications: lab to pilot and manufacturing scale chromatography for small molecules, peptides, lipids, linkers and HP API workflows