ultra-high-performance liquid chromatograph / high-performance liquid / for pharmaceutical applications / for biodiesel
LC-4000 Series



  • Type:

    ultra-high-performance liquid, high-performance liquid

  • Applications:

    for pharmaceutical applications, for biodiesel, for the food industry, laboratory

  • Detector type:

    UV, fluorescence, PDA, UV/VIS, multi-detector

  • Other characteristics:

    ultra high performance (UHPC), with auto-sampler, preparative


The LC-4000 Series is the latest in a long history of innovative HPLC systems developed by JASCO reaching all the way back to the start of commercial HPLC in the early 1970s.

The concept of the integrated LC-4000 series HPLC provides key separation platforms at 50MPa, 70MPa and 130MPa which correspond to conventional HPLC, the increasingly popular Rapid Analysis (Fast HPLC) and sub 2um U-HPLC respectively.

Each platform is supplied with a dedicated pump and autosampler matched to the operating pressure and share detectors optimized for high-speed 100Hz acquisition and the narrow peak shapes common to both Fast HPLC and U-HPLC.

In the LC-4000 series, SSQD technology (Slow Suction, Quick Delivery) has been re-developed, with a completely new solvent delivery mechanism offering the highest stability in solvent delivery across the entire analytical flow rate range used in the PU-4100 Fast HPLC and PU-4200 U-HPLC pump models.

A wide range of high sensitive detectors includes UV-Vis (Dual wavelength), Diode Array, Fluorescence, Refractive Index, Chiral Detector and the world’s unique Circular Dichroism Detector for Liquid Chromatography.

The new LC-4000 Series includes pumps for semi-preparative and preparative HPLC applications that can be coupled with prep-scale autosampler, detectors with flow cell optimized for high-flow rates and fraction collector fully control by ChromNAV 2.0.