Centrifugal partition chromatography system CPC Modeler

laboratoryfor pharmaceutical applicationsprocess

Purification Method Development Platform The CPC Modeler is a desktop-sized CPC platform, which combines an intuitive method development engine with tailor-made semi-preparative chromatographic equipment. The CPC Modeler combines an in-silico method-development engine with semi-preparative chromatographic equipment. Every part of the CPC Modeler, from software to hardware, has been designed to support research and preparative method development. Laboratories, researchers, and preparative chemists can use the platform to predict, test, validate scalable purification methods. The platform offers a mg to g/cycle loading capacity, while also offering the possibility to scale-up production. The CPC Modeler platform consists of three devices: • The Benchtop CPC: A laboratory-scale CPC device with a mg to g/cycle loading capacity, 250 ml column capacity, and 5-50 ml flow rate. • The CPC Simulator: Software solution to predict and visualize purification outcomes for a wide range of molecules in diverse suitable solvent systems. • Liquid delivery and detection devices: Essential components for fraction collection, analysis, and liquid delivery. The platform comes with an integrated GMP-compliant software suite and parallel the CPC Simulator tool, enables users to design and optimize purification methods in-silico before conducting live experiments. By leveraging a comprehensive digital library of scientific data and chemical compound information, researchers can streamline method development and accelerate the pace of discovery.