Structural analysis system Intabio ZT

The Intabio ZT system couples icIEF separation and UV detection with high-resolution mass spectrometry for peak identification. Cut out risk, cut out information gaps. Gain multiple pieces of critical data up front. Accelerate candidate selection by achieving separation, quantitation, and direct identification of biopharmaceutical charge variants and their proteoforms with icIEF-UV/MS via the Intabio ZT system. Comprehensive proteoform identification in minutes The process of identifying individual charge variant components and interpreting their structural differences conventionally takes weeks and requires the use of multiple instruments, with multiple manual steps. With the Intabio ZT system - separation, quantitation and identification of individual charge variants can be achieved in minutes on a single platform. Leverage key analytical functions with microfluidic chip-based technology The Intabio ZT cartridge enables key analytical functions using proprietary microfluidic chip-based integrated icIEF-UV/MS technology. Separation of charge variants with imaged capillary isoelectric focusing (icIEF) Quantitation with real-time UV detection Electrospray ionization for further mass spectrometry identification Enable a more detailed characterization approach by leveraging the enhanced capabilities of the powerful ZenoTOF 7600 system with EAD fragmentation technology. Maintain data continuity with a single workflow producing one, accessible dataset, where UV peaks correlate with MS peaks. Let Biologics Explorer software do the heavy lifting with pre-built workflows for charge variant analysis.