Scientific research electrophoresis system MultiNA II MCE-301

for laboratory

Overview
The MultiNA II MCE-301 is a microchip electrophoresis system that automates DNA and RNA quality-control workflows. It replaces manual steps with a standardized digital QC process using reusable microchips and dedicated software to reduce hands-on time, late QC failures and operating costs.

Key benefits

• Reliable sample quality
  Automated microchip electrophoresis with RNA Integrity Index (RII) and an optional High-Sensitivity kit for sensitive DNA/RNA evaluation.
• Simple and intuitive operation
  Guided workflows in the software, removable sample racks and automatic sample dilution reduce manual handling and errors.
• Smart and sustainable QC
  Reusable chips and reduced energy and purified-water consumption lower consumable use and laboratory resource demands.

Workflow and operation
Register the analysis schedule, load samples and reagents into the removable tray, insert the tray and start automatic analysis. The instrument performs dispensing, separation, detection and rinsing automatically while the software displays results successively for immediate review and confirmation.

Notable functions

• Automated sample dilution
  Automatic dilution to preset factors (5×, 10×, 20×); dilution supported for up to 48 samples (separate tubes for diluted samples required).
• Adding samples during analysis
  System can be paused to add samples; up to 120 additions supported during a run.
• Reorder gel images
  Gel images can be rearranged independently of analysis order for reporting and review.
• Comparison with past data
  Load and display historical data (including data from MCE-202) alongside current results for comparison (some reagent kits may be excluded).
• Calibration curves
  Automatic size and concentration prediction using calibration curves and internal standards for objective numeric results.
• Intuitive data analysis
  Electropherogram views, size-prediction overlays and application-specific processing tools in the software.

Enhanced analysis functions

• RNA
  Automatic calculation of RNA Integrity Index (RII); correlation with other indices shows R2 ≥ 0.95.
• mRNA analysis
  Purity and mixture analysis demonstrated for mRNA samples (examples: Cas9 and EPO mixtures).
• DNA
  DNA fingerprinting functions with automatic presence/absence calls and grouped result listings.
• NGS library QC
  Smear analysis and High-Sensitivity kit enable evaluation of library size distribution and concentration down to approximately 5 pg/µL.
• Genome editing support
  Grouping analysis and molar concentration ratio tools for workflows such as HMA, Cel-I and PCR-RFLP; detection and quantitative evaluation of deletion mutations.

User-friendly design

• Intuitive software with visual guides and image reordering for streamlined data review.
• Removable sample rack supports up to 96 plates and mixed loading of up to two reagent kit types.

ECO functions / Energy & water savings
The MultiNA II reduces laboratory resource use versus the previous model: approximately 30% lower power consumption, more than 40% less purified-water use for rinsing, ~15% smaller footprint and ~27% reduced height (with front door open), lowering liquid waste and easing integration in constrained labs.

Application highlights
Application notes and technical guides support workflows such as NGS library QC, analysis of LNP-encapsulated mRNA, RNA quality evaluation (RII), heteroduplex mobility assays, allergen gene analysis, PCR‑RFLP species identification and other molecular biology procedures.

Documents (examples)
Analysis of Allergen Genes in Food Using a Microchip Electrophoresis System | 2026-03-17
Rapid and Simple Analysis of LNP-Encapsulated mRNA Using a Microchip Electrophoresis System | 2026-03-17
Identification of Thunnus Species by PCR-RFLP Method Using MultiNA II | 2026-02-27

Technical specifications

• Model name: MultiNA II MCE-301
• Platform: automated microchip electrophoresis for DNA/RNA QC
• Sample rack capacity: removable rack holds up to 96 plates
• Automatic dilution: supported factors 5×, 10×, 20×; dilution supported for up to 48 samples (dispense tubes required separately)
• During-run additions: up to 120 samples can be added during analysis (system pause)
• High-sensitivity detection: library concentrations measurable down to ~5 pg/µL with High-Sensitivity kit
• RNA Integrity Index (RII): system-calculated; correlation vs other systems R2 ≥ 0.95
• Compatibility: data from previous model (MCE-202) can be loaded for comparison (some reagent kits not supported)
• Reagent flexibility: up to 2 reagent kit types can be loaded in mixed arrangement
• Operation time: analysis can be started after ~10 minutes of preparation; supports overnight runs
• Energy savings: ~30% lower power consumption vs previous model
• Water savings: purified-water consumption for rinsing reduced to <60% vs previous model (>40% reduction)
• Footprint: ~15% smaller footprint and 27% shorter height than previous model (with front door open)