The Agilent 400-DS Dissolution Apparatus 7 has set the performance standard specifically for small-scale drug-release testing on medical devices like drug eluting stents (DES). It has different custom and standard holders that are available for testing of leachables, extractables, wound-care products, catheters, contact lenses, pacemaker leads, combinatorial products and more.
It is considered the first dissolution apparatus built specifically for small-scale dissolution testing including combination drug products that meet the tedious requirements of USP Apparatus 7. The 400-DS also complies with 21 CFR Part 11 guidelines and is able to bring an unbeaten level of efficiency, throughput and convenience to R&D and quality control operations.
Performs automated small-volume dissolution testingusing as little as 3 mL media volume in either 5 or 10 mL sample cells
Saves time by simultaneously testing up to 13 samples, or 12 samples and a control or standard, while providing users direct visibility of each dissolution cell
Maintains temperature control through internal temperature probes and external heating jackets; no water bath is required
Minimizes evaporation through the fully closed system
Integrated syringe pump and autosampler save valuable bench space
Offers automated media addition/removal of up to 5 different types of media through a port on the bottom of the cell
Enables sample holder reciprocation through an externally controlled magnetic plate and supports between 1 and 35 dips per minute (DPM) to best match your requirements