Fed-batch bioreactor Ondalis

batchperfusionlaboratory

Product overview
Ondalis is a single-use wave rocking bioreactor system designed for sensitive and high-density cell culture processes. The wave motion delivers low shear while ensuring homogeneous mixing and precise control of critical parameters. Integrated single-use workflows and the Bio-Bag Integrity Test support validated, scalable production from research to small-scale manufacturing.

Highlights

• Single-use design for safe, rapid turnover and reduced contamination risk
• Low shear environment suited to fragile cell lines
• Applicable to batch, fed-batch and perfusion processes
• Scalable from lab to pilot/production volumes
• Integrated Bio-Bag Integrity Test for process security

Features

• Gentle, uniform wave movement for optimal nutrient and gas exchange
• No cleaning or sterilization effort thanks to single-use setup
• Intuitive BioSCADA interface with visualization of culture parameters
• CFR-21 Part 11 compliant data handling and user management
• Precise control of temperature, rocking angle, gas flow and CO2
• Flexible scale range ideal for R&D and small production runs
• Plug-and-work design requiring no complex installation
• Compatible with high-cell-density batch, fed-batch and perfusion cultures
• Compact footprint for laboratory environments

Services

• Installation and commissioning
• Basic user training
• Process and technical documentation
• Preventive maintenance and calibration
• Spare parts and consumables supply
• Technical support and application assistance

Technical Details

• Working volumes: from 0.2 L to 35 L (compatible bag sizes 2 L to 50 L)
• Rocking speed: adjustable from 2 to 40 rpm
• Rocking angle: adjustable from 2° to 12°
• Temperature control: ambient to 40 °C (precision ± 0.2 °C)
• Gas flow control: integrated 0 to 1000 ml/min
• CO2 measurement range: 0% to 15% (accuracy ± 0.3%)
• pH control range: 6.0 to 8.0 (accuracy ± 0.1 pH)
• DO control range: 0% to 100% (accuracy ± 3%)
• Weight measurement: integrated load cells, 1 g accuracy
• Safety: integrated pressure monitoring and alarms