Automatic preparation system MOPROCESS®

in-linemultifor the pharmaceutical industry

Product overview
Inline buffer preparation systems enable on-demand dilution and multi-component buffer formulation directly in the process line, reducing footprint and minimizing tank-based batch preparation. MOPROCESS® systems are designed for downstream biopharmaceutical processing where continuous or frequent buffer generation is required.

Inline dilution system
Concentrated mother solutions are diluted on demand with WFI or purified water using flow-feedback control to deliver target concentrations. Real-time flow control ensures accurate volumetric dilution while minimizing hold-up volumes.

Inline conditioning system
Multiple concentrated feeds (acid, base, salt solutions, water, additives) are blended inline to obtain the required buffer composition. pH and conductivity are monitored and adjusted via closed-loop feedback to maintain formulation stability during preparation.

Applications

• Downstream processing for monoclonal antibodies and recombinant proteins
• Vaccine and antibiotic production
• Insulin and blood product processing

Technical parameters
Parameter diagrams are available on the product page; no numeric technical parameters are listed in the page content.

Features / technical specifications

• Functionality: Inline dilution (mother solution dilution) and inline conditioning (multi-component buffer formulation)
• Control & monitoring: Online pH and conductivity monitoring with feedback control
• Inputs: Multiple concentrated mother solutions (acidic, alkaline, salt, WFI, additives)
• Control strategy: Real-time adjustment based on pH and conductivity feedback
• Scalability: Suitable from laboratory scale to production scale
• Benefits: Reduced floor space for buffer preparation and storage; decreased tank maintenance and cleaning/validation burden