Total organic carbon analyzer TOC-1000e

beveragefoodfor pharmaceutical products

Overview
eTOC (TOC-1000e) is an on-line Total Organic Carbon (TOC) analyzer for monitoring ultra-pure water. It uses a mercury-free excimer lamp and Shimadzu's "Active-Path" optical design to provide sensitive measurements in a compact, environmentally friendly enclosure. The system applies a UV-oxidation/conductivity detection method compliant with major pharmacopeias and includes security functions for regulatory compliance.

Key points

• Mercury-free excimer lamp for UV oxidation.
• "Active-Path" optical/flow design to maximize lamp effectiveness and sensitivity.
• Compact, lightweight enclosure with large colour touch panel for visibility and operation.
• Typically maintenance-free for one year under specified conditions; tool-free maintenance design.
• Supports conditioned standard solutions and a vial sampler for up to four solutions for on-site calibration and qualification.
• Export data to USB in readable formats; remote data viewing/acquisition via web browser.
• Security functions supporting FDA 21 CFR Part 11 (user authentication, audit trail) and transfer to LabSolutions™ database.

Performance note
The TOC-1000e delivers high sensitivity with reported detection limits down to 0.1 µg/L, suitable for online monitoring of ultra-pure water.

Applications / Documents
Process monitoring of PEM H2 electrolysis feed water using TOC-1000e | 2025-02-02; TOC system suitability test using TOC-1000e according to USP 643 | 2020-10-27; Online measurement of ultra-pure water using TOC-1000e | 2020-10-27; eTOC series brochure available.

Characteristics / technical specifications

• Measurement principle: UV oxidation – conductivity detection.
• Lamp: Mercury-free excimer lamp.
• Optical/flow design: "Active-Path" technology.
• Display/UI: Large colour touch panel.
• Maintenance: Typically maintenance-free for one year (condition: measurement period ≥ 5 minutes); tool-free maintenance.
• Calibration/validation: Supports conditioned standard solutions and vial sampler (up to 4 solutions).
• Data handling: USB export; remote access via web browser; transfer to LabSolutions™.
• Regulatory compliance: Supports USP/EP and includes FDA 21 CFR Part 11 functions.
• Reported detection: Limits reported down to 0.1 µg/L.
• Typical use: Online TOC analysis of ultra-pure water in pharmaceutical, semiconductor, medical device, food & beverage, chemical and precision machinery industries.