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Many years of experience and know-how in the production of lyophilizers means we can offer individual application driven solutions to customers demands. We are able to offer variations and flexibility in mechanical and electronical design (plant layout, sterilization methods like SIP and H2O2, vacuum-, refrigeration- and control systems, CIP, ice condenser manufacturer capacity, shelf area) to meet customers´ specification.
All units from Christ fulfil highest standards on materials used and functional safety and ca be extended for future operations. Modern control electronics simplify user operation and allow the storage of programs, so that processes can be reproduced. The units comply to international regulations such as GMP, FDA, GAMP, PIC.
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| Based on over 50 years of experience, Martin Christ presents a comprehensive product range covering routine applications as well as reliable equipment for individual and product specific drying processes. The newly introduced lyophilizers with LDplus- and LSC-controller set new standards for flexibility and process control. The modular accessory line allows for individual system configurations adaptable to almost every freeze-drying application. Two different drying techniques provide a solution to most lyophilisation challenges. |
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Pilot-scale freeze drying with ice condenser manufacturers capacities between 6 and 12 kg are specially designed for drying processes similar to large-scale production units. Prefreezing and drying will be realized on liquid temperature controlled shelves inside the separate drying chamber (double-chamber-system). Due to the temperature control of the stainless steel shelves (via a synthetic heat-transfer medium), these pilot systems fulfil the highest standards of the pharmaceutical and biotech industries. The CHRIST pilot-scale freeze professional dryers can be upgrated or modified to meet the individual requirements for process optimization and scale-up, e.g. with a comprehensive and flexible measurement- and control-system (e. g. lyo-resistance-control, weighing-system, process monitoring). If necessary, a decontamination with H2O2 is possible as well as an integration into isolator systems (glove-box).
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From Lab to Production
A range range of large scale vacuum concentrators to suit your needs is available, from development and pilot scale bulk tray and vial industrial dryers to full size production systems.
Hull and VirTis Benchmark systems provide large scale production and pilot batch production for Pharmaceutical applications. Systems are available with CiP, SiP and 21 CFR part 11 compliant software.
VirTis range of freeze driers extends downwards from pilot scale to laboratory sytems with all sizes in between. A range of options, shelf numbers, and software is available.
VirTis offers a versatile range of laboratory freeze dryers, from the basic bench top model to a high performance combined bench top shelf and flask dryer.
Benck Top K series are standard flask dryers, some models have the option to add shelves containing a small number of vials. Manual stoppering is available with these models.
The Advantage and Advantage Plus are shelf driers, with optional stoppering, which also provide four cocks to accomdate flasks, enabling excellent use of bench space. The Advantage Plus has fluid cooled shelves which brings production scale capabilites to the lab bench for the first time! |
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VirTis offers a versatile range of laboratory freeze driers, from the basic bench top model to a high performance combined bench top shelf and flask dryer.
Benck Top K series are standard flask professional dryers, some models have the option to add shelves containing a small number of vials. Manual stoppering is available with these models.
The Advantage and Advantage Plus are shelf driers, with optional stoppering, which also provide four cocks to accomdate flasks, enabling excellent use of bench space. The Advantage Plus has fluid cooled shelves which brings production scale capabilites to the lab bench for the first time! |
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FTS LyoStar II is the pinnacle of R&D freeze drier engineering. Designed and built like a production freeze drier, yet the size of a R&D Pilot model. The LyoStar II with breakthrough “Smart Freeze-Industrial dryer™ Technology” will revolutionize the way development scientists generate freeze-drying cycles.
The LyoStar II has everything that you would expect, superior shelf mapping, fast shelf freezing, stoppering for vials, easy to use sample thief, and incredible software which reduces the average R&D cycle time from 64 days to 13.
SMART Freeze-Dryer Technology is a patented system that puts
the experience of the world’s top lyophilisation scientists into an
easy-to-use cycle development tool. Developed exclusively with
leading academics SMART Freeze-Dryer Technology relates to the automated process driver of using manometric temperature measurement and is designed to eliminate the trial-and-error approach normally involved in developing new lyophilization cycles. It enables experts and novices alike to develop new cycles quickly, while also ensuring that those cycles are elegant and efficient. The SMART tools provide instant feedback on important product data - such as product resistance, heat flow, and product thickness — that was previously unavailable.
• Shelf pull-down rate from ambient to -40ºC in less than 25 minutes
• Temperature resolution in 0.1ºC increments
• Powerful scroll compressors with only three moving parts (with two-year warranty)
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For freeze drying of bacteria, enzymes and similar sensitive products
Superior stainless steel lyophilizers
Full steam sterilization: SIP
Cleaning In Place: CIP
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