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Based on over 50 years of experience, Martin Christ presents a comprehensive product range covering routine applications as well as reliable equipment for individual and product specific drying processes. The newly introduced freeze dryers with LDplus- and LSC-controller set new standards for flexibility and process control. The modular accessory line allows for individual system configurations adaptable to almost every freeze-drying application. Two different drying techniques provide a solution to most lyophilisation challenges.
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Pilot-scale freeze dryers with ice condenser capacities between 6 and 12 kg are specially designed for drying processes similar to large-scale production units. Prefreezing and drying will be realized on liquid temperature controlled shelves inside the separate drying chamber (double-chamber-system). Due to the temperature control of the stainless steel shelves (via a synthetic heat-transfer medium), these pilot systems fulfil the highest standards of the pharmaceutical and biotech industries. The CHRIST pilot-scale freeze dryers can be upgrated or modified to meet the individual requirements for process optimization and scale-up, e.g. with a comprehensive and flexible measurement- and control-system (e. g. lyo-resistance-control, weighing-system, process monitoring). If necessary, a decontamination with H2O2 is possible as well as an integration into isolator systems (glove-box).
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Many years of experience and know-how in the production of freeze dryers means we can offer individual application driven solutions to customers demands. We are able to offer variations and flexibility in mechanical and electronical design (plant layout, sterilization methods like SIP and H2O2, vacuum-, refrigeration- and control systems, CIP, ice condenser capacity, shelf area) to meet customers´ specification.
All units from Christ fulfil highest standards on materials used and functional safety and ca be extended for future operations. Modern control electronics simplify user operation and allow the storage of programs, so that processes can be reproduced. The units comply to international regulations such as GMP, FDA, GAMP, PIC.
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VirTis offers a versatile range of laboratory freeze dryers, from the basic bench top model to a high performance combined bench top shelf and flask dryer.
Benck Top K series are standard flask dryers, some models have the option to add shelves containing a small number of vials. Manual stoppering is available with these models.
The Advantage and Advantage Plus are shelf driers, with optional stoppering, which also provide four valves to accomdate flasks, enabling excellent use of bench space. The Advantage Plus has fluid cooled shelves which brings production scale capabilites to the lab bench for the first time!
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The freeze-/vacuum dryer developed by Merk Process contains multiple drying processes for fluid products as well as granule products. Equipped with extensive measurement systems this plant is the ideal pilot plant for laboratory.
Custom balance between contact/infrared and microwave heating for each
product
Possibility of drying granule products or fluid, pasty products in batch or
continous operation
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FTS LyoStar II is the pinnacle of R&D freeze dryer engineering. Designed and built like a production freeze drier, yet the size of a R&D Pilot model. The LyoStar II with breakthrough “Smart Freeze-Dryer™ Technology” will revolutionize the way development scientists generate freeze-drying cycles.
The LyoStar II has everything that you would expect, superior shelf mapping, fast shelf freezing, stoppering for vials, easy to use sample thief, and incredible software which reduces the average R&D cycle time from 64 days to 13.
SMART Freeze-Dryer Technology is a patented system that puts
the experience of the world’s top lyophilisation scientists into an
easy-to-use cycle development tool. Developed exclusively with
leading academics SMART Freeze-Dryer Technology relates to the automated process control of using manometric temperature measurement and is designed to eliminate the trial-and-error approach normally involved in developing new lyophilization cycles. It enables experts and novices alike to develop new cycles quickly, while also ensuring that those cycles are elegant and efficient. The SMART tools provide instant feedback on important product data - such as product resistance, heat flow, and product thickness — that was previously unavailable.
• Shelf pull-down rate from ambient to -40ºC in less than 25 minutes
• Temperature resolution in 0.1ºC increments
• Powerful scroll compressors with only three moving parts (with two-year warranty)
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The freeze drying pilot plant RAY 1 is used in the food and beverage industries for small-scale production of market samples and for pilot testing of new products prior to full-scale production. The RAY 1 also features easy cleaning and maintenance.
The RAYTM 1 plant is also used in bacterial and pharmaceutical applications.
The pilot plant RAYTM 1 is operated via a PC control system. Parameters are monitored and stored during the freeze drying process to provide full documentation of the process. This makes it possible to repeat the test with the same freeze drying characteristics.
Modem for remote control or troubleshooting can be integrated in the PC system.
Test runs with the RAYTM 1 provide excellent data for scaling up to industrial production, either in one of the Atlas RAYTM batch freeze dryers or in a CONRADTM continuous freeze drying plant.
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From Lab to Production
A range range of large scale freeze dryers to suit your needs is available, from development and pilot scale bulk tray and vial dryers to full size production systems.
Hull and VirTis Benchmark systems provide large scale production and pilot batch production for Pharmaceutical applications. Systems are available with CiP, SiP and 21 CFR part 11 compliant software.
VirTis range of freeze driers extends downwards from pilot scale to laboratory sytems with all sizes in between. A range of options, shelf numbers, and software is available.
VirTis offers a versatile range of laboratory freeze dryers, from the basic bench top model to a high performance combined bench top shelf and flask dryer.
Benck Top K series are standard flask dryers, some models have the option to add shelves containing a small number of vials. Manual stoppering is available with these models.
The Advantage and Advantage Plus are shelf driers, with optional stoppering, which also provide four valves to accomdate flasks, enabling excellent use of bench space. The Advantage Plus has fluid cooled shelves which brings production scale capabilites to the lab bench for the first time!
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Our Heto and Savant freeze dryers range from 1.5 to 20 liters to accommodate small, simple, laboratory bench top requirements, to larger systems with greater programming capabilities. Interchangeable accessories support flasks, vials, ampules, trays, and microplates.
Products
- Heto PowerDry LL1500 Freeze Dryer
- Heto PowerDry LL3000 Freeze Dryer
- Heto PowerDry PL3000 Freeze Dryer
- Heto PowerDry PL6000 Freeze Dryer
- Heto PowerDry PL9000 Freeze Dryer
- ModulyoD Freeze Dryer
- SuperModulyo Freeze Dryer
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For freeze drying of bacteria, enzymes and similar sensitive products.
* Superior stainless steel freeze dryers
* Full steam sterilization: SIP
* Cleaning In Place: CIP
RAY™- S DESIGN
The RAY™-S cabinets are made of stainless steel throughout. Only the heating plates are made of anodized aluminum to obtain optimal heat transfer by means of radiation.
The RAY™-S cabinets are designed as cylindrical vessels with special attention to the demand for full steam sterilization (SIP) and cleaning in place (CIP).
The RAY™-S series is available in the same sizes as the RAY™ series.
GEA Niro has developed a pilot plant; the RAY™-1. Here it is possible to establish drying curves, weightless curves and temperature developments during the freeze drying process. A plant that is a must if you want to develop new freeze dried products.
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Lyophilisateurs Thermo Scientific
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The lyophilisateurs Thermo Scientific decline themselves in a complete range of apparatuses and accessories, which ensure you a fast and effective preparation of your samples.
The ranges Thermo Scientific Heto and Thermo Scientific Savant go from 1,5 to 20 liters to adapt as well to the small samples of laboratory as to the largest systems which require greater programming.
Of -55°C with -110°C, the lyophilisateurs Thermo Scientific, are compact and very simple to use.
Our ranges also cover the accessories and consumable associated with the use of our apparatuses: bulbs, tubes, bottles, microphone-plates, plates.
More on the lyophilisateurs Thermo Scientific, promotions in progress, to contact our customer service, or to download booklets, go on:
www.thermo.com
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