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quasi-elastic light scattering macromolecular characterization instrument

Quasi-elastic light scattering macromolecular characterization instrument


The WyattQELS (Quasi-Elastic-Light-Scattering) instrument contains a real time digital correlator. The correlator measures the autocorrelation function of the intensity signal from any one angle of the DAWN or from the 90 degree location of the miniDAWN. The correlator then calculates the hydrodynamic radius at each elution time in order to provide hydrodynamic radii over an entire chromatographic peak.

Unlike many other dynamic light scattering instruments, the WyattQELS detector, when interfaced to the DAWN, allows one to measure correlation as a function of angle. Particles larger than 150nm may scatter relatively little light at 90 degrees because of intra-particle interface or "Mie scattering".


Features
Multiple Tau correlation design with a fixed range of channel from 480 nsec to ~1 hour (real-time).
No sample time optimization required!
A total of 264 channels with input data format of 5 bit for the first 16 channels, the the sample time doubles every 8 channels and the data width is incremented 1 bit for every set of channels. No pre-scaling required.


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