Mass spectrometer ion source DIP

The DirectProbe (DIP) add-on for the Bruker APCI II and APPI II ion sources allows direct analysis of liquid and solid samples without tedious sample preparation. In routine organic synthesis analyses, it simplifies identification and characterization of chemical reaction products without compromising sensitivity. Extremely sensitive down to the sub-ng range of pure substance - amount not visible at all ! Minimum sample preparation Direct analysis of liquid & solid samples Short analysis time No memory due to single-use glass tubes Applications Fields of applications are General Chemistry → Synthesis control Manual quality control of solids (Pharma, oil, explosives) Customs → Drugs of abuse, explosives Homeland security Environmental Thermal degradation processes (plastic production) Classical routine analysis (e.g. confirmation of sum formula) Direct injection Probe with APCI for ID synthetic compounds This example shows the unambiguos identification of a synthetic compound using the autoMSn capability of an amaZon SL ion trap system. During the vaporization of solid (refer to TIC insert) data-dependent MS2 and MS3 spectra are taken. Note that after a simple neutral loss in MS2, MS3 provides rich structural information. Samples were kindly provided by SiChem GmbH, Bremen, Germany. Direct injection Probe with APPI for QC in Production The example shows the results of a quick manual QC and Comparison of petroleum cuts with an amaZon SL. The three candidates gas oil vacuum gas oil and vacuum residue are clearly distinguishable without any sample preparation and no memory-effect due to single use sample tubes.