Innovation and application of detection technology for the residue on evaporation in purified water
Abstract
The residue-on-evaporation method of purified water is to detect the quality of residue on evaporation solids obtained after 100 mL of purified water is evaporated and dried. The difficulty is that the operator needs to repeat the operation to achieve the 0.3mg constant weight value required by the Chinese Pharmacopoeia. The traditional test method has the shortcomings of low efficiency and manual duty. After long-term practice and repeated verification, it adopts an integrated automatic structure design, equipped with rapid water bath evaporation and gas balance technology, which can realize automatic feeding, water bath evaporation, blast drying and cooling balance, constant temperature weighing five-in-one automatic test. Through the repeatability experiment and gradient design experiment, the results show that: 2 rounds of weighing can reach a constant weight error value of 0.3mg, when the scalar amount is 9.4mg/100mL, the precision (RSD) is 0.73%, and the accuracy of the gradient design experiment is high. There is no deviation between parallel samples. Conclusion: After the innovation of the residue on evaporation detection technology of purified water, the test time to reach constant mass value is short, the operation is simple, and the data accuracy and precision are good.
Key words: purified water; residue on evaporation; constant mass; automated test