Static light scattering nanoparticle size analyzer Zetasizer Lab

dynamic light scatteringelectrophoretic light scatteringfor the food industry

Overview

• Zetasizer Lab is an entry-level Dynamic Light Scattering (DLS) instrument for particle size, zeta potential and molecular weight analysis, designed for routine laboratory characterisation with advanced analysis modes and data-quality feedback via ZS Xplorer.

Key features

• DLS particle size analysis: indicative range 0.3 nm to 15 μm (standard high-accuracy range to 10 μm; extended range with accessories).
• Zeta potential by M3-PALS and constant-current zeta mode for nanoparticles and colloids; zeta size range 3.8 nm–100 μm.
• Static Light Scattering (90°) for molecular weight (Debye plot) analysis.
• Supports low-volume disposable capillary cell enabling size measurements from 3 μL; zeta minimum volume 20 μL (patented diffusion barrier technique).
• On-site upgrade path to Zetasizer Pro or Zetasizer Ultra models.
• ZS Xplorer software gives immediate feedback on data quality and guided workflows.

Applications

• Academic research: particle/molecular size and zeta potential characterisation.
• Biosciences and pharmaceuticals: stability, aggregation and formulation development (proteins, colloids, viral vectors).
• Nanomaterials: size distribution and dispersion quality assessment.
• Food, coatings, inks and industrial R&D: dispersion and emulsion control, QC.

Accessories & options

• Low-volume disposable capillary sizing cell (ZSU1002) and folded disposable capillaries (DTS1070).
• Sample Assistant autosampler for batch measurements.
• MPT-3 autotitrator for automated pH titration workflows.
• Various cuvettes and high-concentration kits, quartz low-volume cuvettes.

Specifications (selected)
Measurement principle (size): Classical 90° Dynamic Light Scattering
Measurement angles: 90°, 13° (water as dispersant)
Particle size range: 0.3 nm – 15 μm (indicative data for >10 μm with Extended Size Range accessory)
Minimum sample volume (size): 3 μL (low-volume capillary cell)
Concentration range (size): example minima — Blue Label: 1 mg/mL (15 kDa protein); Red Label: 0.3 mg/mL (15 kDa protein). Maximum sample concentration: up to 40% w/v (sample dependent)

Zeta measurement principle: M3-PALS (mixed-mode phase analysis light scattering)
Zeta size range: 3.8 nm – 100 μm
Minimum sample volume (zeta): 20 μL (patented diffusion barrier technique)
Sample conductivity (zeta): up to 260 mS/cm

Static Light Scattering (molecular weight): Debye plot capability
Molecular weight range (SLS): Lab Red: ~300 Da – 20 MDa; Lab Blue: ~980 Da – 20 MDa; accuracy ±10%

System: Detector: Avalanche Photodiode (APD)
Laser: He‑Ne (633 nm); Blue label: 4 mW max; Red label: 10 mW max
Temperature control: 0 °C – 120 °C (dry nitrogen purge required below dew point); accuracy examples: 0.1 °C at 25 °C
Dimensions (W x D x H): 322 mm x 565 mm x 245 mm
Weight: 19 kg
Power: AC 100–240 V, 50–60 Hz, 4.0 A; Power consumption: Max 100 W, Typical 45 W
Interface: USB 2.0 or higher
Compliance / standards: ISO22412, ISO13099-2, relevant USP and ASTM monographs

Software & compliance

• ZS Xplorer analytical software: guided workflows and instant data-quality feedback.
• Compatible with OmniTrust for regulated environments and data integrity features.
• On-site upgradeability and software updates available.