Fixed sprayer iMLayer™ AERO

liquidselectricautomatic

Overview
The iMLayer™ AERO is an automatic sprayer designed for MALDI imaging. The system integrates a moving sample stage that advances at a controlled speed while keeping a constant distance from the spray nozzle, enabling repeatable and uniform matrix deposition. Multiple passes laminate the sample with fine matrix crystals, enabling high sensitivity and high spatial resolution suited to laboratory and clinical research workflows.

Key points

• Automatic sprayer for MALDI imaging
• Moving sample stage with controlled speed and constant nozzle distance
• Stable, repeated spraying produces laminated fine matrix crystals
• Enables high sensitivity and high spatial resolution imaging

Features

• Imaging with high reproducibility
• Both sensitivity and spatial resolution achieved
• Applicable to pretreatments beyond matrix coatings

Work flow / Illustrations
Workflow diagrams and overview images on the product page illustrate sample staging, nozzle positioning and the spraying process to facilitate integration into MALDI sample preparation protocols.

Downloads

• Brochure: iMLayer AERO - Automatic Sprayer for MALDI Imaging [PDF / 616KB]

Applications
Sample preparation for MALDI mass imaging, including tissue sections and organoid analyses.

• Mass Imaging Analysis of Organoids on iMScope QT [PDF / 1.35MB] — Creation Date: 2025-09-29

Technical specifications

• Brand: Shimadzu
• Model: iMLayer™ AERO
• Type: Automatic sprayer for MALDI imaging
• Primary function: Automated matrix spraying / matrix vapor deposition
• Sample handling: Moving sample stage with controlled speed
• Nozzle control: Maintains constant distance from spray nozzle for uniform coating
• Resulting performance: Lamination of fine matrix crystals for high sensitivity and high spatial resolution
• Applicable pretreatments: Matrix coatings and other sample pretreatment procedures