Optical microscope iMScope™ QT

for analysisfor researchclinical

Overview
The iMScope QT is an imaging mass microscope combining optical microscopy with MALDI mass spectrometry, designed for high‑resolution, high‑speed mass spectrometry imaging. Compatible with LCMS‑Q‑TOF integration, it delivers qualitative, quantitative and spatial information from a single platform.

Total System for MS Imaging Analysis
MS imaging workflows include sample pretreatment, data acquisition and data analysis. Optimized procedures and system integration at each step accelerate research and improve reproducibility of spatial molecular data.

Key Points for MS Imaging

• Support for end‑to‑end workflows: pretreatment, acquisition and analysis tailored to MS imaging studies.
• Correlative analysis: fusion of morphological and chemical distribution information for comprehensive interpretation.

Features

• Combined analysis: Correlative overlay of MS images with optical microscope observations to link histology and molecular distribution.
• Quantification and distribution: Integration with LCMS‑Q‑TOF enables qualitative and quantitative LC‑MS data alongside spatial MSI information.
• High resolution, speed and sensitivity: Acquisition optimized for high spatial resolution, rapid throughput and sensitive detection with streamlined data processing.

Videos

• Mass Spectrometry Imaging: Paving the Way for the Next Generation
• iMScope QT introduction to tissue sample workflows

Downloads

• iMScope QT - Imaging Mass Microscope [PDF]
• Multimodal Imaging System [PDF]
• iMLayer [PDF]

Applications
Representative application notes include organoid mass imaging, clinical spatial metabolomics using multi‑derivatization strategies, and spatial distribution studies in plant tissues (e.g., gossypol in cotton).

Trademark
iMScope is a trademark of Shimadzu Corporation.

Technical specifications

• Model: iMScope QT
• Product type: Imaging Mass Microscope (MALDI‑MS imaging)
• Integration: Designed for integration with LCMS‑Q‑TOF for combined qualitative/quantitative analyses
• Workflow support: Pretreatment, data acquisition and data analysis for MS imaging
• Key performance: Focus on high spatial resolution, rapid acquisition speed and high sensitivity for MSI
• Documentation: Product brochures, application notes and videos available (PDF)