Liquid filter-dryer

for solidsfabricvacuum

Overview
Büchi glass Nutsche filters for pilot plants, kilo-labs and scale-up laboratories. Mobile and stationary systems with vessel volumes from 10 to 300 L designed for solid–liquid separation, filtration, drying and downstream purification in corrosive environments and under inert atmosphere.

Technical data (table)
Filtration vessel sizes: 10, 30, 50, 100, 140, 300 L
Operating pressure: full vacuum (-1.0 bar FV) to +0.5 bar
Temperature range: -60 °C to +150 °C (design options up to 200 °C)
Filter cloth: mesh 8–115 µm
Materials: borosilicate glass 3.3, PTFE, PFA, ETFE

Typical applications

• Filtration / Separation
• Solid-phase peptide synthesis (SPPS)
• Drying
• Chromatography
• Purification
• Cannabis extraction (solvent extraction)
• Crystallization
• Cannabinoid extraction
• Ion exchange
• Cannabis extract purification
• Peptide synthesis
• Cannabis winterization

About the Nutsche filter
Büchi Nutsche filters enable controlled solid/liquid separation under vacuum or slight positive pressure and can be integrated with reactors for downstream separation after synthesis. The slurry is charged into the filter; solids are retained by the filter cloth forming a cake while the filtrate exits via the bottom outlet valve. Filtration time can be reduced by mechanically compressing or smoothing the cake using the height-adjustable stirrer. Cake discharge is performed from the top after opening the cover and lowering the glass vessel with the lifting device; the same device provides access to the filter cloth for cleaning or replacement. Inert-material options and sealed/containment variants allow processing under inert atmosphere and compatibility with a wide range of solvents and acids. Clean-room and high-containment designs are available for demanding regulatory or process requirements.

Standard package

• Glass filter vessel
• ETFE-coated cover plate with ports for slurry feed, nitrogen, etc.
• PTFE bottom plate with filter cloth
• Mobile stainless-steel frame with lifting device
• High corrosion resistance
• FDA-conform components
• cGMP-capable
• Complete documentation

Standard options

• Manual stirrer in stainless steel, Hastelloy or with inert coating
• ATEX-compliant stirrer drive with adjustable speed
• CIP-capable design
• Heating jacket for drying
• IQ / OQ / PQ

Technical specifications

• Available vessel sizes: 10, 30, 50, 100, 140, 300 L
• Operating pressure range: full vacuum (-1.0 bar FV) up to +0.5 bar
• Temperature range: -60 °C to +150 °C (up to 200 °C depending on design)
• Filter cloth mesh range: 8–115 µm
• Materials: borosilicate glass 3.3, PTFE, PFA, ETFE coatings
• Mobile stainless-steel frame with lifting device for vessel and bottom-plate handling
• Options: ATEX drives, pneumatic or height-adjustable agitator, heating jacket, CIP-ready designs
• Compliance: cGMP, FDA-conform components; full documentation available