OverviewBuchiglas engineers and delivers complete production-scale reactor systems for chemical and pharmaceutical processes with nominal capacities from 250 to 10,000 L. Systems combine glass-lined (enameled) steel or Hastelloy® reactor vessels with borosilicate 3.3 glass overheads and the proprietary buchiflex flexible glass piping to meet cGMP and ATEX-related requirements.
Reactor summaryType: glass-lined (enameled) steel reactor (DIN AE / BE type)
Volume range: 250 – 10,000 L
Pressure (glass distillation overhead): -1.0 (full vacuum) to +0.5 bar (higher reactor pressures possible using split-off valves)
Temperature range: -60 °C (down to -90 °C in special designs) to +200 °C
Materials: borosilicate glass 3.3, glass-lined steel, PTFE, PFA, Hastelloy® (C22/C276), tantalum, titanium, SiC
Technology and engineering highlightsSystems pair robust glass-lined or Hastelloy® vessels with borosilicate glass distillation heads to provide corrosion-resistant process paths and visual process monitoring at production scale. Design focus includes full customization of auxiliary equipment (dosing, weighing, solvent recovery), modular integration, short campaign changeovers and maintenance-friendly assemblies using buchiflex flexible connections.
Typical process equipment applications- Chemical synthesis (organic & inorganic)
- Extraction & evaporation
- Purification & crystallization
- Distillation, reflux and azeotropic distillation
- Cryogenic / low-temperature reactions
- Solvent and acid recovery, recycling & purification
- APIs and HPAPIs
- Agrochemicals, fine & specialty chemicals
- Flavors, fragrances, pigments & dyes
- Detergents, coatings, adhesives
- Electronic and semiconductor chemicals
- Specialty polymers, battery chemicals, catalysts, precious metals
Key features & advantages- Full customization: tailored integration of reactor, dosing pumps, weighing systems and auxiliary units to match process requirements.
- Flexible piping: buchiflex glass connection system (DN15 – DN150) for stress-free connections and rapid changeovers.
- Corrosion resistance: material combinations (glass-lined steel or Hastelloy®, borosilicate glass, fluoropolymers, ceramics) for aggressive media.
- Process visibility: borosilicate glass overheads enable visual monitoring at production scale.
Technical specifications- Volume: >250 – 10,000 L (DIN AE / BE types)
- Pressure (glass distillation overhead): -1.0 to +0.5 bar (options for higher reactor pressures)
- Temperature range: -60 °C (to -90 °C in special designs) to +200 °C
- Materials: borosilicate 3.3, glass-lined steel, PTFE, PFA, Hastelloy® (C22/C276), tantalum, titanium, SiC
- Piping: buchiflex flexible glass connections (DN15 – DN150)
- Compliance: engineered for cGMP and ATEX where required