Pilot freeze dryer LyoStar 4.0

for the pharmaceutical industryfor chemicals products

The Hull LyoStar 4.0 R&D and Process Development Freeze Dryer is designed and built to speed your biologic to market, with significant advancements in freeze dryer engineering. Based on a full-scale production freeze dryer to support rapid-scale-up, the Hull LyoStar 4.0 is a pilot-scale lyophilizer offering superior shelf mapping and rapid shelf freezing for unmatched process accuracy and reliability. Including a cutting-edge suite of Process Analytical Technology (PAT) tools, SP’s Line of Sight™ suite of technologies helps you overcome critical lyophilization challenges during development, scale-up, and manufacture of a biologic. These technologies include: LyoFlux® TDLAS Sensors for vapor mass flow measurement AutoMTM/SMART™ Freeze Dryer Technology, a primary drying cycle optimization tool ControLyo® Nucleation Technology giving pinpoint control of freezing point Tempris® Wireless Sensors for real-time product temperature measurement Application Examples • Formulation Development & Stability Studies • Cycle Optimization & Scale-up • Lyophilization of Product with Organic Solvents in Addition to Water • Laboratory Research & Development Freeze-Drying • Diagnostic Kits • 96-Well Plates • Serum Bottles & Vials Features & Benefits • Get to market faster – sophisticated instrumentation set, advanced cycle development, and optimization features decrease cycle development time and conserve valuable API • You can never be too informed – LyoStar 4.0 provides more product and process information such as dried layer resistance, heat flow, mass transfer, and how different freezing protocols impact cake resistance