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... is taken up as a main theme. As a solution, Supercritical Fluid Chromatography (SFC) is drawing attention from many researchers. Since the separation capacity of SFC is higher than ...
... SFE – SFC – MS platform unifies quick and easy on-line sample preparation with state-of-the-art chromatographic analysis and high sensitivity detection. Nexera UC improves your analytical workflow through an unprecedented ...
... Prep 100q SFC System provides high-throughput, semi-preparative to preparative scale purification, meeting the increased demand for higher productivity, greater flexibility, and lower costs per sample. The only open-bed ...
A supercritical fluid chromatograph (SFC) is a specific type of liquid chromatograph. Its particularity is a supercritical fluid mobile phase. These fluids lack a clear boundary between the liquid and gas phases.
ApplicationsThese devices are used to analyze substances that cannot be handled by either a gas or a liquid chromatograph.
TechnologiesSuch instruments resemble high-pressure liquid chromatographs. However, the columns are a little shorter to avoid a decrease in pressure. A backpressure regulator ensures sufficient pressure to maintain the supercritical state. As in gas chromatographs, column temperature is maintained by a furnace.
How to chooseChoice of stationary phase depends primarily on the mixture to be separated. The sensor at the column outlet must be suitable for the specific mobile phase employed.
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