About the SECUREFILL 25TThe SECUREFILL 25T is a capsule filling machine engineered for contained handling of highly potent active pharmaceutical ingredients (HPAPIs). Built as a monoblock SS316L containment unit with HEPA filtration, rapid transfer port (RTP) and glove ports maintained under negative pressure, it is certified for OEB up to level 4 and optimized for small to medium production batches.
Applications- Containment filling of pellets, tablets, micro-tablets, powders, soft gels and combinations into capsules
- Manufacture of capsules containing oncology, hormonal, antiviral and other HPAPI formulations
Key features & benefitsMonoblock SS316L containment with HEPA filtration, RTP and glove ports — Ensures complete operator and environmental containment (OEL 1–10 µg/m³).
Provision for contained charging and discharging — Enables integrated closed transfer for upstream and downstream processes.
Wet-in-place (WIP) system for wetting suspended particles in the pharma zone — Reduces airborne dust, protects operators and simplifies cleaning.
Certified for highly potent and cytotoxic drugs (OEB up to level 4) — Supports safe production of HPAPI-containing therapies.
Integration-ready for check-weighers, metal detectors, capsule sorters and de-dusters under containment — Facilitates a controlled, inspected production line.
Features / Benefits table (extracted)Monoblock SS316L with HEPA, RTP, glove ports, negative pressure — Complete containment; prevents operator exposure (OEL 1–10 µg/m³).
Contained charging/discharging — Integrated containment for upstream/downstream operations.
Wet-in-place system — Wetting of suspended particles to protect operator and ease cleaning.
OEB certified up to level 4 — Suitable for HPAPI and cytotoxic drug production.
Integration capability with inspection and sorting ancillaries — Ensures product quality and safety.
Technical specifications- Model: SECUREFILL 25T
- Capsule size: 00 - 5
- Maximum speed: 25,000 capsules/hr
- OEL / OEB: 1–10 µg/m³ (certified OEB up to level 4)
- Construction: Monoblock SS316L containment structure with HEPA filtration, RTP and glove ports
- Containment: Negative pressure maintained in pharma zone
- Cleaning: Wet-in-place system for suspended particle control and cleaning facilitation
- Integration: Designed for integration with check-weighers, metal detectors, capsule sorters and de-dusters under containment