Disintegration tester PTZ series

automatictabletfor the pharmaceutical industry

Tablet disintegration testing instruments are widely used in the pharmaceutical industry to evaluate the disintegration characteristics of formulations and the quality control of different dosage forms. All Pharma Test tablet and capsule disintegration testers are fully compliant with the current USP and EP Pharmacopeia and support both A-type and B-type baskets for regular or larger samples. They feature a stainless-steel housing, to be more GMP compliant than painted housing designs. Often these instruments are used in QC and IPC laboratories where most of the other equipment uses stainless steel as well. This way the Pharma Test instruments certainly do not look out of place. The disintegration basket which holds the glass tubes and discs, is placed into a metal holder and held by a magnet. The instrument detects if a basket is inserted or not. The illuminated LC-display shows status information, like the elapsed testing time. The disintegration basket is moved up and down by 55mm (each way) at a rate of 30 times per minute. At test start it is moved smoothly into the testing medium. The instrument’s heating system using a circulation pump warms the water inside the Plexiglas water bath up to the programmed target temperature, i.e. 37°C. A second sensor is used as a safety device which switches off the heater in case the temperature should rise outside the limit. A flow sensor, a thermal fuse and a thermal switch provide additional safety features to protect the system from overheating. The bath target temperature can be freely adjusted. Using the supplied temperature probe, the medium temperature can always be checked.