Fluidized bed granulator GT X•ONE

wetfor the pharmaceutical industryhigh-shear

About the GT X•ONE series The GT X•ONE series is ACG’s integrated solution for wet granulation and pelletisation, combining high‑shear mixer units (HSM X•ONE) with fluid‑bed equipment (FBE X•ONE / FBC X•ONE). Designed at ACG’s Design Centre in Mülheim, Germany, the series is engineered to reduce waste and downtime while improving product consistency, safety and process ergonomics for production lines operating under strict GMP and regulatory constraints.

Key product concept GT X•ONE unites the strengths of high‑shear mixing and fluid‑bed processing into a compact, highly contained granulation line. The architecture supports closed‑loop product transfer, enhanced containment and easy integration of upstream/downstream equipment for seamless process control and fast changeovers.

Features & Benefits A 12‑bar pressure shock‑resistant system incorporating the MOST™ (Maximum Operator Safety Technology) concept, FSA‑approved and ATEX‑compliant — no mechanical deformation in case of a pressure‑shock event; production can be resumed quickly; safer working environment thanks to a non‑vented fully contained design.
X•ONE inflatable seals and QASV (Quick Action Stop Valves) — extended seal life due to lower operating pressures; safety maintained at pressures from approx. 4.5 bar.
Compact machine footprint — reduces floorspace requirements by up to ~50% compared with conventional arrangements.
Through‑the‑wall construction — enables clear separation between processing and technical areas for easier maintenance, cleaning and GMP compliance.
Enclosed product handling (gravity or vacuum charging options, customisable) — closed‑loop transfer points with smooth material flow, reduced residues and dust exposure; minimises manual intervention and supports GMP requirements.
Superior WIP (wash‑in‑place) capability — eliminates dead spots and addresses crevices and hard‑to‑reach areas for fast, effective cleaning and rapid changeover.
ACG’s exclusive process control system — ATEX, GAMP 5 and 21 CFR Part 11 compliant; provides secure, intuitive monitoring and control of the granulation train.

Features & Benefits (tabular extraction) 12‑bar pressure shock‑resistant system with MOST™ — Benefit: no mechanical deformation after pressure shock; rapid production resume; improved operational safety due to non‑vented containment.
X•ONE inflatable seals and QASV — Benefit: longer seal life from reduced operating pressures; safe operation from ~4.5 bar.
Compact footprint — Benefit: up to ~50% reduction in floorspace.
Through‑the‑wall construction — Benefit: separation of processing and technical areas; easier maintenance and better GMP compliance.
Enclosed product handling (gravity/vacuum) — Benefit: closed‑loop transfer, reduced leftovers and dust, smoother material flow.
Superior WIP capability — Benefit: elimination of dead spots; easy washing and quick changeover.
ACG process control system — Benefit: compliant with ATEX, GAMP 5 and 21 CFR Part 11; intuitive and secure system control.

Technical specifications

• Series: GT X•ONE series (integration of HSM X•ONE and FBE/FBC X•ONE)
• Design origin: ACG Design Centre, Mülheim, Germany
• Pressure shock resistance: 12‑bar pressure shock‑resistant system
• Safety concept: MOST™ (Maximum Operator Safety Technology), FSA approved
• Compliance: ATEX (Directive 2014/34/EU); process control system compliant with GAMP 5 and 21 CFR Part 11
• Containment: Non‑vented, fully contained design; enclosed product handling options (gravity or vacuum charging)
• Sealing & safety valves: X•ONE inflatable seals and QASV (Quick Action Stop Valves)
• Minimum safety operating pressure: safety features effective at low pressures (~4.5 bar)
• Footprint: compact design — up to ~50% reduction in floorspace compared to conventional arrangements
• Construction option: through‑the‑wall configuration to separate processing and technical areas
• Cleaning: Superior WIP (wash‑in‑place) capability; elimination of dead spots and ease of changeover
• Process control: ACG’s exclusive control system for secure, intuitive monitoring and control