Wet granulator HSM 300 X·ONE

rotorknifefor pharmaceutical applications

About the HSM 300 X·ONE
Advanced high-shear mixer granulator designed for small production batches, delivering faster processing and narrow particle-size distribution while ensuring content uniformity in the dry mix. Equipped with ACG process control system and MOST™ (Maximum Operator Safety Technology). Suitable for standalone operation or full integration in a granulation train.

Applications

• Wet granulation
• Mixing

Features & Benefits
Unique product bowl geometry | Maintains a roping flow regime for uniform mixing and faster process stabilisation via linear scalability.
Z-shaped impeller and multi-blade chopper | Ensures uniform binder distribution, optimised particle-size distribution and reduced accumulation on the bowl.
12-bar pressure shock‑resistant system (MOST™) — FSA-approved; ATEX compliant | Prevents mechanical deformation after pressure shock; enables rapid production restart; fully contained non‑vented design improves operator safety.
Multiple charging/discharging and WIP options | Greater flexibility to suit formulation needs.
ACG process control system | Intuitive, secure monitoring and control; compliant with ATEX (2014/34/EU), GAMP 5 and 21 CFR Part 11.

Also available (models / capacities)

• QUEST HSM II — 2 L, 5 L, 10 L (small scale)
• QUEST HSM III — 15 L, 30 L, 65 L (small scale)
• HSM 150 X·ONE — 150 L
• HSM 300 X·ONE — 90–240 L (working volume dependent on bulk density)
• HSM 400 X·ONE — 400 L
• HSM 600 X·ONE — 600 L
• HSM 800 X·ONE — 800 L
• HSM 1200 X·ONE — 1,200 L
• HSM 2000 X·ONE — 2,000 L (extra large scale)

Technical specifications

• Working volume (min): 90 L
• Working volume (max): 240 L (dependent on bulk density)
• 12‑bar pressure shock‑resistant design (MOST™)
• Non‑vented, fully contained construction
• Z-shaped impeller and multi-blade chopper
• Unique product bowl geometry for roping flow and linear scalability
• Multiple charging/discharging options and wash-in-place (WIP)
• ACG process control system — ATEX, GAMP 5 and 21 CFR Part 11 compliant
• Designed for small production batches; standalone or integrated in granulation trains
• Primary applications: wet granulation and mixing