Wet granulator QUEST HSM III

for laboratoryfor pharmaceutical applicationshigh-shear

About the QUEST HSM III
The QUEST HSM III is a high-shear mixer granulator for laboratory and pilot R&D that delivers faster processing, narrow particle-size distribution and improved dry-mix content uniformity. It integrates ACG's process control system and the MOST™ (Maximum Operator Safety Technology) concept. The standalone, mobile plug-and-play design enables rapid setup and supports cGMP environments.

Applications

• Mixing
• Hot-melt granulation
• Wet granulation

Features & Benefits

• 12-bar pressure shock‑resistant system with MOST™ (FSA‑approved, ATEX compliant) — avoids mechanical deformation after a pressure event and allows rapid production restart in a fully contained, non‑vented design.
• ACG process control system — ATEX, GAMP 5 and 21 CFR Part 11 compliant; provides secure, intuitive monitoring and control.
• Z-shaped impeller blades — ensure optimal material flow in and out of the shear zone, reducing accumulation and sticking.
• Multi‑blade straight chopper — breaks lumps during granule formation, prevents dead zones and promotes uniform binder distribution.
• Standalone mobile plug‑and‑play system — rapid deployment within the laboratory or pilot area.
• Interchangeable bowls (15 L, 30 L, 65 L) — enable flexible batch sizes.

Technical specifications

• Model: QUEST HSM III
• Manufacturer / Brand: ACG
• Bowl sizes (interchangeable): 15 L / 30 L / 65 L
• Working volumes* (15 L / 30 L / 65 L): Min 4.5 L / 9 L / 19.5 L; Max 9 L / 18 L / 39 L
• Pressure shock resistance: up to 12 bar (MOST™ concept)
• Control: ACG process control system (ATEX, GAMP 5, 21 CFR Part 11)
• Impeller: Z-shaped blades
• Chopper: multi‑blade straight chopper
• Intended use: Lab and pilot R&D; cGMP environments

Also available

• QUEST HSM II — 2 L, 5 L, 10 L (small scale)
• HSM 150 X·ONE — 150 L
• HSM 300 X·ONE — 300 L
• HSM 400 X·ONE — 400 L
• HSM 600 X·ONE — 600 L
• HSM 800 X·ONE — 800 L
• HSM 1200 X·ONE — 1200 L
• HSM 2000 X·ONE — 2000 L (extra large scale)

Note
*Working volumes depend on bulk density.