Calculation server ESC4000A-E10

networkGPUgraphics processing unit

Summary
2U single-socket GPU server designed for AI training, inference and compute-dense workloads. Powered by AMD EPYC 7003 & 7002 processors, the system supports multiple GPU and accelerator configurations, PCIe Gen4 expansion, front-accessible NVMe and comprehensive remote management.

Key Features

• Supports AMD EPYC™ 7003 & 7002 series (up to 64 cores / 128 threads; CPUs up to 280 W TDP)
• GPU-optimized chassis: up to 4 double-slot GPUs or 8 single-slot GPUs (with PLX SKU)
• Up to eleven PCIe® Gen4 slots for high-bandwidth expansion
• OCP 3.0, NVMe and M.2 front-panel options for flexible I/O
• Redundant Platinum power supplies (1600W or 2200W) and hot-plug fans
• Embedded ASMB9-iKVM and ASUS Control Center for out-of-band and in-band management

PCIe 4.0 expansion
Multiple PCIe Gen4 slots support GPUs, HBAs/RAID, NICs and InfiniBand cards. Riser options include butterfly and front riser configurations to accommodate varied accelerator layouts.

GPU and accelerator support
Compatible with NVIDIA® A100, Tesla® T4, Quadro®, AMD Instinct™ MI100 and Xilinx Alveo (Alveo U50 qualified). Supports NVIDIA NVLink bridge where applicable for scaled GPU interconnect.

Flexible front panel design
Front-accessible options include up to four NVMe drives, OCP 3.0 mezzanine, and onboard M.2 (22110) for OS. Hyper M.2 adapter and HBA/RAID cards supported via PCIe Gen4 slots.

Scalable storage design
Chassis accommodates up to eight 3.5" or 2.5" drives and up to four NVMe SSDs. Onboard M.2 slot supports system boot; optional hyper M.2 card enables additional NVMe capacity.

Performance Boost and thermal technologies
Includes ASUS Performance Boost (workload presets, Core Optimizer, Engine Boost) and ASUS Thermal Radar 2.0 with multiple sensors and zoned fan control to optimize performance and thermals for dense GPU configurations.

Power management
ASUS Power Balancer dynamically manages CPU power and frequency distribution to improve performance-per-watt in mixed workloads.

Management and remote features
Embedded ASMB9-iKVM provides remote BIOS update, KVM, fan control and system logging. ASUS Control Center enables centralized in-band monitoring and software deployment.

Technical specifications

• Model: ESC4000A-E10
• Form factor: 2U single-socket GPU server
• Processor support: AMD EPYC™ 7003 & 7002 series (up to 280 W TDP)
• Memory: 8-channel DDR4 support (refer to vendor for configuration)
• GPU support: up to 4 double-slot or 8 single-slot GPUs (PLX SKU)
• Accelerator support: Xilinx Alveo U50 qualified
• PCIe: up to eleven PCIe® Gen4 slots; multiple riser options
• Storage: up to 8 x 3.5"/2.5" drives; up to 4 x front NVMe; 1 x onboard M.2 (22110)
• Network: dual LAN and OCP 3.0 support (cards up to 200 Gbps referenced)
• Power supply: redundant 1600W or 2200W Platinum PSUs
• Cooling: hot-plug fans; ASUS Thermal Radar 2.0
• Management: ASMB9-iKVM (out-of-band); ASUS Control Center (in-band)
• Use cases: AI training & inference, HPC, virtualization, rendering, data analytics

Product status
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