Quadrupole spectrometer LCMS-8060

massMS/MSfor the pharmaceutical industry

Product Type
Triple quadrupole LC-MS/MS (Liquid Chromatograph coupled to a triple quadrupole mass spectrometer)

Overview
The LCMS-8060 integrates an optimized ion guide (UF-Qarray) and an enhanced ion transport optical system to significantly increase ion sampling efficiency and focusing. Sensitivity is improved approximately 3× compared with the LCMS-8050 while preserving high-speed MS/MS performance. This combination delivers superior sensitivity and very high throughput, enabling rapid detection of ultra-trace components in complex biological and environmental matrices.

Key Features

• Sensitivity: UF-Qarray ion guide and optimized ion transport provide meaningful gains in signal intensity and quantitative performance (~3× vs LCMS-8050).
• Speed: Fast MS/MS acquisition and rapid polarity switching support high-throughput LC workflows.
• Solutions: Proven results for challenging bioanalytical tasks, e.g., high-sensitivity quantitation of intact catecholamines in human plasma.
• Stability: Long-term robustness validated by extended high-volume testing (thousands of femtogram-level injections).

Applications
Trace quantitative analysis in complex matrices, including clinical and bioanalytical studies, pharmaceutical ADME/PK, environmental monitoring and food safety testing that require ultra-trace sensitivity and high throughput.

Technical specifications

• Model: LCMS-8060
• Series: UFMS
• Instrument type: Triple quadrupole LC-MS/MS
• Key technologies: UF-Qarray ion guide; enhanced ion transport optical system for improved ion sampling and focusing
• Sensitivity improvement: Approximately 3× vs LCMS-8050 (as reported)
• Performance: High-speed MS/MS acquisition with rapid polarity switching for high sample throughput
• Robustness: Designed for continuous high-throughput operation; validated long-term stability
• Manufacturer / Brand: Shimadzu