Quadrupole spectrometer LCMS-8045

opticallaboratoryfood

Overview
Equipped with a heated ESI probe, the LCMS-8045 delivers high sensitivity and reliable long-term performance. The heated ESI probe, high-temperature heating block, desolvation line (DL) and drying gas promote efficient desolvation and reduce the risk of liquid droplet contamination entering the MS unit. The system reaches a maximum scan speed of 30,000 u/sec and a polarity switching speed of 5 msec, enabling ultra-high-speed quantitative analyses. The LCMS-8045 is suitable for food safety, environmental and routine quantitative applications and can be upgraded to the LCMS-8060.

Key feature highlights

• Heated ESI probe and heated capillary sample introduction to improve desolvation.
• High-temperature heating block and desolvation line (DL) to reduce droplet contamination.
• Drying gas and proprietary ion transfer/focusing optics to maximize sensitivity and limit contamination.
• High scan speed (30,000 u/sec) and fast polarity switching (5 msec) for high-throughput quantitation.
• Maintenance-friendly design: quick replacement of desolvation line and ESI capillary.

Features (summary)

• Combines high sensitivity with ultra-high-speed detection.
• Consistent performance supported by the MS interface and ion optics design.
• Redesigned ionization unit for simplified maintenance and reduced downtime.

Applications (documents table)
Determination of NTTP in Sitagliptin by LCMS-8045 — 2024-06-18
Quantification of Four Azido Impurities in Losartan Potassium API using LCMS-8045 — 2023-10-29
Released glycan analysis of trastuzumab biosimilar using LCMS-9030 — 2023-10-29

Downloads (selected brochures/manuals)
Shimadzu Analytical and Measuring Instruments (brochure)
LCMS-TQ RX Series (brochure)
LC/MS/MS Method Package for Glycosaminoglycans - For LabSolutions LCMS (method package brochure)
Analytical Solutions for Analysis of Polymer Additives (brochure)
LC/MS/MS Method Package for PFAS in Drinking Water - For LabSolutions LCMS (method package brochure)
LCMS Family Brochure UFMS ULTRA FAST MASS SPECTROMETRY - Shimadzu’s Mass Spectrometry Solutions (family brochure)
LCMS-8045 - Liquid Chromatograph Mass Spectrometer (product brochure)

Technical documents (selected)
LC/MS/MS Analysis for Restricted Chemicals in Textiles — 2019-09-04
Fully Automated LC-MS/MS Analysis of Anticoagulants Using a Stable Isotope Labelled Internal Standards — 2019-08-27
Highly sensitive and rapid analysis of synthetic dyes in sea food by LC/MS/MS — 2017-06-15

Technical specifications

• Heated ESI probe (high-sensitivity source)
• Heated capillary sample introduction
• High-temperature heating block
• Desolvation line (DL) and replaceable ESI capillary for easy maintenance
• Drying gas and proprietary ion transfer/focusing optics to minimize contamination
• Scan speed: 30,000 u/sec
• Polarity switching speed: 5 msec
• Typical applications: food safety testing, environmental analysis, quantitative analyses
• Upgradeable to LCMS-8060