Mass spectrometer LCMS-2050

quadrupolefor analysisfor laboratory

Overview
The LCMS-2050 single quadrupole LC‑MS detector combines LC detector usability with mass spectrometry functions in a compact design for direct integration with LC/HPLC/UHPLC systems. It supports analysis of compounds across a wide polarity and mass range, provides high-speed scanning and trace-level sensitivity, and includes automated performance checks (Performance Concierge), the Mass-it function for mass annotation of UV chromatograms and Analytical Intelligence tools for streamlined data review. Eco-conscious features reduce energy consumption and routine maintenance needs.

Key selling points

• Designed for seamless LC integration to simplify installation and workflows
• Mass-it adds mass information directly to UV chromatograms for faster identification
• Automated checks and easy maintenance to maximize uptime and reduce operating costs

Features (high-level)

• Single quadrupole MS optimized for LC coupling
• High-speed scan capability (up to 15,000 u/s) suitable for UHPLC
• Wide mass range (m/z 2–2000) and fast polarity switching for diverse analytes
• Dual ionization source (DUIS) for flexible ionization modes
• Mass-it and Analytical Intelligence software functions for enhanced data interpretation
• Compact footprint and energy-saving design for laboratory space efficiency
• Automatic instrument performance monitoring (Performance Concierge)

Documents & resources (available on product page)

• LCMS-2050 brochure (product brochure)
• Improving Liquid Chromatography Workflows with Mass Spectrometry (infographic)
• Technical Background for the LCMS-2050, a Compact Mass Detector for LC
• Interpretation of LC Chromatograms Facilitated by Mass Detection and the Mass-it™ Function
• Application note: Determination of N-Nitroso-Nebivolol in Nebivolol Drug Substance by LCMS-2050

Awards & recognition

• Red Dot Design Award for Product Design 2023
• Good Design Award

Technical specifications

• Instrument type: single quadrupole LC‑MS
• Scan speed: 15,000 u/s
• Mass range: m/z 2–2000
• Resolution: 0.7 u
• Polarity switching: 10 ms
• Ion source: DUIS (dual ionization)
• Software: Mass-it™, Analytical Intelligence, LabSolutions LCMS control
• Compatibility: designed for LC/HPLC/UHPLC integration