Automatic harvester C2MAP™

for cell cultures

Overview
The C2MAP™ System is an LC/MS/MS cell culture media analysis platform that automates pretreatment through measurement of culture supernatant samples and generates temporal change profiles for up to 95 culture supernatant components. Its optimized LC/MS/MS simultaneous analysis method supports optimization of animal cell culture conditions by monitoring consumption and depletion of media components and variations in metabolites secreted by cells.

Visualization
Temporal changes in component concentrations are visualized using the dedicated viewer software C2MAP TRENDS, which plots time-series graphs for each measured compound.

Key features

• Automated workflow from pretreatment to measurement for culture supernatant samples
• Optimized LC/MS/MS simultaneous analysis covering a broad range of compounds
• Capability to obtain temporal change profiles for up to 95 components
• Modular pretreatment units operable independently of the LC/MS/MS instrument
• Dedicated C2MAP TRENDS viewer for time‑course visualization and exportable graphs

Documents referenced on this page

• Brochure: Shimadzu Analytical and Measuring Instruments (PDF, 11.13MB)
• Guide to Biopharmaceutical Solutions (PDF, 7.69MB)

Usage note
For Research Use Only. Not for use in diagnostic procedures.

Technical characteristics / specifications

• Platform: LC/MS/MS simultaneous analysis method
• Profiling capability: temporal change profiles for up to 95 culture supernatant components
• Automation: automated workflow from pretreatment to measurement
• Software: C2MAP TRENDS dedicated viewer for time‑course graphing
• Modularity: pretreatment modules operable independently of LC/MS/MS
• Applications: monitoring consumption/depletion of media components and variations in secreted metabolites to optimize culture conditions