Membrane ultra-filtration unit BIO-TFF series

platewith filter pumpfor liquids

Overview

• Suitable for 0.1 and 0.5 m² membrane packages
• Automatic pressure and flow control (TMP control)
• Four-piston diaphragm pump (Germany/China brands)
• Imported flowmeter (Germany/Japan)
• High-accuracy peristaltic pump for recirculation
• AISI 316/AISI 316L single-layer or jacketed tank
• Optional stirring, weighing, protein concentration, pH and conductivity electrodes

Product Details
The system is designed for downstream processes of biological products including purification, clarification, concentration and buffer exchange. It features a semiautomatic workflow with automated TMP regulation, automated concentration and diafiltration collection, and continuous data recording for batch traceability.

System Advantage

• Optimized piping layout to minimize circulation and hold-up volumes
• Pipeline design compliant with ASME BPE standards
• Sensor flow cell and multi-channel valve body to eliminate dead zones
• Modular construction for easy loading/unloading and flexible lab deployment
• Multiple optional modules to meet advanced usage needs
• Imported flowmeter for accurate concentrate and permeate monitoring
• Optional multi-sensor packages (conductivity, pH, UV, protein concentration)
• Integrated BIO-TFF Intelix® OS with independent display and operation interfaces
• User-friendly operation: set key parameters and run; supports multi-endpoint control and unattended operation
• Automated TMP control with alarms, online monitoring, data logging and curve display

Main Specifications
Supported membrane package area: 0.1 m² – 0.5 m²
Circulation tank: AISI 316L stainless steel; volume: 10 L; stirring speed: 0–1000 rpm
Primary pump: Four-piston diaphragm pump; speed: 0–3000 rpm; flow: 0–180 L/h
Peristaltic pump: speed 0–60 rpm; flow up to 186 L/h
Feed flow: 0–3 L/min
Working pressure: 0–6 bar
Process temperature range: 0–65 °C
Minimum circulation volume: 120 ml
Hold-up volume: 29 ml
Fluid interface: 1/2"
Fluid-contact materials: AISI 316L, PTFE, EPDM

Optional List
ITEM CODE: DESCRIPTION
BIOTFFAUT001: Flat membrane package (0.1 m², 0.5 m²)
BIOTFFAUT002: Hollow fiber column
BIOTFFAUT003: Protein concentration monitoring
BIOTFFAUT004: Conductivity electrode
BIOTFFAUT005: pH electrode
BIOTFFAUT006: Tank stirring system
BIOTFFAUT007: Weight system
BIOTFFAUT008: Jacketed tank
BIOTFFAUT009: UV detector

Technical Specifications

• Model / SKU: BIO-TFF Automatic
• Supported membrane area: 0.1 m² – 0.5 m²
• Circulation tank material: AISI 316L stainless steel
• Circulation tank volume: 10 L
• Stirring speed (tank): 0–1000 rpm
• Primary pump: Four-piston diaphragm pump (0–3000 rpm), flow 0–180 L/h
• Peristaltic pump: 0–60 rpm, flow up to 186 L/h
• Feed flow range: 0–3 L/min
• Operating pressure range: 0–6 bar
• Process temperature range: 0–65 °C
• Minimum circulation volume: 120 ml
• Hold-up volume: 29 ml
• Fluid connections/interface: 1/2"
• Fluid-contact materials: AISI 316L, PTFE, EPDM
• Optional sensors/modules: conductivity, pH, UV, protein concentration, weight system, jacketed tank, hollow fiber or flat membrane packages
• Control: BIO-TFF Intelix® OS with automated TMP control, data logging and alarms