Evaporative light-scattering detector ELSD-LT III

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Overview
The ELSD-LT III is an evaporative light scattering detector (ELSD) for HPLC/UHPLC that enables detection of analytes with little or no UV absorption, including carbohydrates, lipids, surfactants and synthetic polymers. It incorporates low-temperature evaporation technology to broaden analyte scope, Analytical Intelligence functions to extend dynamic range, and control via LabSolutions™ software. Some volatile compounds are excluded.

Features

• Universal detection principle — measures light scattered by microparticles of target components remaining after evaporation of the mobile phase; suitable for compounds with poor UV absorption or masked by mobile phase background.
• Low-temperature evaporation technology — enables analysis of semi-volatile analytes while reducing thermal degradation.
• High-power laser with photometric control — provides stable sensitivity and reliable signal over long operation periods.
• Wide dynamic range through Analytical Intelligence — extends usable quantitative range and simplifies method workflows.
• Compact, space-saving design — approximately 2/3 the height of the previous model; can be mounted on top of LC units to reduce bench footprint.
• Software integration — operable and controllable using LabSolutions™ for data acquisition and method transfer.

Downloads

• ELSD-LT III brochure [PDF / 2.72MB]
• Efficient Method Development of Lipid Nanoparticle Components Using ELSD [PDF / 611.86KB]
• Simultaneous Analysis of Monosaccharides and Oligosaccharides in Beer Using ELSD-LT III [PDF / 530.93KB]
• Quantitative Analysis of Glucosylceramide in Commercial Supplement [PDF / 228.25KB]

Applications

• UHPLC analysis of sugars
• Analysis of chondroitin
• Method development for lipid nanoparticle components
• Simultaneous analysis of monosaccharides and oligosaccharides in beer
• Quantitative analysis of glucosylceramide in supplements

Characteristics / Technical specifications

• Detector type: Evaporative Light Scattering Detector (ELSD) for HPLC/UHPLC
• Detectable analytes: compounds with little or no UV absorption (carbohydrates, lipids, surfactants, synthetic polymers)
• Limitation: excludes some volatile compounds
• Evaporation: low-temperature evaporation technology for semi-volatile analytes
• Light source: high-power laser with photometric control for stable sensitivity
• Dynamic range: wide, enhanced by Analytical Intelligence features
• Software: compatible with LabSolutions™
• Design: compact, mountable on LC units to save bench space