Fluorescence detector RF-20A

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Overview
The RF-20A and RF-20Axs fluorescence detectors extend the Prominence series' baseline performance, delivering very high sensitivity, simplified maintenance and validation support features. They are suitable for a wide range of HPLC applications from routine analysis to high‑performance and ultra‑fast separations.

Key features

• World-class sensitivity: New optical system design provides markedly improved sensitivity for trace fluorescence detection.
• Cell temperature control improves reproducibility (RF-20Axs): Fluorescence intensity can decrease as temperature rises; a fluctuation of about 1°C near room temperature may cause ~5% intensity variation for some compounds.
• Support for ultra-fast analysis: 10 ms response time enables tracking of sharp peaks from ultra-fast separations without loss of resolution.
• Easy maintenance: Xenon lamp and flow cell are replaceable from the front panel. Lamp replacement requires no positional adjustment and the flow cell can be replaced tool-free.

Applications (selected documents)
Quantitative Analysis of Aflatoxin in Edible Nuts by Using High-Performance Liquid Chromatography Coupled with Florescence Detector | 2026-01-21
Quantification of Six Porphyrin Biomarkers in Urine Using LC-2050C with Fluorescence Detection | 2024-08-05
Analysis of Functional Components Procyanidins in Apple Juice | 2023-09-26

Technical documents (selected)
RF-20A Fluorescence Detector Basics and Applications | 2022-09-11
Guide to Biopharmaceutical Solutions | 2021-09-01

Specifications

• Detector type: Fluorescence detector (RF-20A and RF-20Axs)
• Fast response time: 10 ms typical response for ultra-fast analysis
• Temperature control: Cell temperature control available on RF-20Axs to improve reproducibility
• Light source: Xenon lamp (front-panel replaceable)
• Flow cell: Front-panel replaceable flow cell, tool-free replacement
• Applications supported: Conventional HPLC through high-performance and ultra-fast analyses