Ultra high-performance liquid chromatograph MT

high-performance liquidfor pharmaceutical applicationsfor impurities analysis

Overview
The i-Series Method Transfer System provides a single integrated LC platform capable of conventional HPLC and rapid UHPLC analysis. It delivers high compatibility with existing LC systems and high-speed methods, enabling reliable migration and transfer of analytical methods between instruments with differing system delay volumes. The system is based on the i-Series platform and integrates LabSolutions™ software with ACTO functionality to streamline method transfer workflows in pharmaceutical development.

Key product points

• Single system supporting both HPLC and UHPLC analyses via dedicated flow lines.
• High reproducibility across LC systems despite differences in system delay volumes.
• Enables migration between UHPLC and HPLC without separate instruments.
• Integrated ACTO function in LabSolutions™ for automated injection timing adjustment.

Features highlighted on the page

• Dual flow-line architecture simplifies method migration by providing separate UHPLC and HPLC delay volumes in one instrument.
• ACTO (Analytical Condition Transfer and Optimization) adjusts injection timings to compensate for system volume differences without editing gradient programs.
• One-button method transfer using ACTO to reduce manual intervention and standardize transfers.
• User-focused design based on the i-Series platform for consistent operability and reliability.

Downloads
Product brochure available in PDF (file size shown on page: 1.28MB).

Technical specifications

• Product type: Method transfer system for liquid chromatography (i-Series MT system).
• Supported analysis modes: HPLC and UHPLC within a single system.
• Architecture: Dual flow lines to match different system delay volumes for UHPLC and HPLC.
• Software: ACTO (Analytical Condition Transfer and Optimization) integrated with LabSolutions™ for injection timing adaptation.
• Operation: Single-button method transfer via ACTO.
• Intended applications: Pharmaceutical development workflows, including process synthesis screening and impurity identification.
• Platform: Based on Shimadzu i-Series instruments for enhanced operability and reliability.