Ultra high-performance liquid chromatograph Nexera™ FV

laboratoryprocessfor pharmaceutical applications

Overview
The Nexera FV is an Ultra High Performance Liquid Chromatograph (UHPLC) designed for automated online analysis from sample collection to data reporting. It automates dissolution testing workflows including dispensing dissolution media, periodic sampling via a flow-through vial, chromatographic analysis and data processing. Based on the Nexera X3 platform and compatible with LabSolutions FV software, the system can operate as a dedicated online monitoring instrument or as a standard UHPLC for high-throughput laboratory workflows.

Key points

• Automates online LC analysis from sample collection to data acquisition and reporting.
• Integrates dissolution media dispensing and periodic sampling to reduce manual intervention.
• Built on the Nexera X3 platform for fast, sensitive and stable chromatography.
• Can serve as a standard UHPLC for general high-throughput analyses.

Features

• Autosampler with flow-through vial for periodic unattended sampling.
• Two selectable analysis modes to match sampling intervals and analysis durations.
• Compatible with online analysis of flow synthesis and batch reaction monitoring.
• Software integration for automated sequence preparation, data processing and report generation.

Applications

• Automated online dissolution testing for pharmaceutical development, quality control and bioequivalence studies.
• Online monitoring of flow synthesis and continuous processes.
• Batch reaction monitoring to reduce cost and risk from manual sampling.
• High-throughput UHPLC workflows in analytical laboratories.

Technical specifications

• Model: Nexera FV
• System type: Ultra High Performance Liquid Chromatograph (UHPLC) for online analysis.
• Platform: Nexera X3.
• Software: Compatible with LabSolutions FV for automation and data analysis.
• Sampling: Autosampler with flow-through vial, periodic sampling from dissolution vessels or reactors.
• Analysis modes: Two selectable modes for varying sampling intervals and analysis times.
• Primary uses: Automated dissolution testing, flow synthesis monitoring, batch reaction monitoring, general UHPLC analysis.